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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERAS
All Species:
6.06
Human Site:
T219
Identified Species:
12.12
UniProt:
Q7Z444
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z444
NP_853510.1
233
25287
T219
A
R
S
C
R
E
K
T
R
H
Q
K
A
T
C
Chimpanzee
Pan troglodytes
XP_528758
339
36402
K326
E
K
M
S
K
D
G
K
K
K
K
K
K
S
K
Rhesus Macaque
Macaca mulatta
XP_001101805
233
25185
A219
A
R
S
C
R
E
K
A
R
H
Q
K
A
T
C
Dog
Lupus familis
XP_548988
233
24926
S219
A
G
A
S
G
D
K
S
R
H
Q
K
A
M
C
Cat
Felis silvestris
Mouse
Mus musculus
Q7TN89
227
24302
T213
V
A
E
S
S
K
K
T
R
H
Q
K
A
V
C
Rat
Rattus norvegicus
Q04970
189
21225
D176
K
K
L
N
S
S
E
D
G
T
Q
G
C
M
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F352
189
21260
D176
K
K
L
N
S
N
E
D
G
N
Q
G
C
M
G
Frog
Xenopus laevis
Q91806
189
21364
D176
K
K
L
D
S
S
E
D
N
N
Q
G
C
I
R
Zebra Danio
Brachydanio rerio
P79737
188
21321
D175
K
K
L
N
S
R
E
D
R
K
Q
G
C
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08646
189
21575
K176
N
K
G
R
R
G
R
K
M
N
K
P
N
R
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P22981
184
20964
D171
R
K
H
R
E
R
H
D
N
N
K
P
Q
K
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q01387
229
25331
G215
S
K
S
E
K
Y
S
G
T
E
K
P
K
R
P
Conservation
Percent
Protein Identity:
100
31.8
99.1
79.4
N.A.
74.6
39.9
N.A.
N.A.
39.9
37.7
40.3
N.A.
35.1
N.A.
35.6
N.A.
Protein Similarity:
100
44.2
99.1
85.4
N.A.
80.6
51.5
N.A.
N.A.
51.9
51.5
51.5
N.A.
51
N.A.
49.3
N.A.
P-Site Identity:
100
6.6
93.3
53.3
N.A.
53.3
6.6
N.A.
N.A.
6.6
6.6
13.3
N.A.
6.6
N.A.
0
N.A.
P-Site Similarity:
100
46.6
93.3
73.3
N.A.
60
20
N.A.
N.A.
26.6
26.6
26.6
N.A.
33.3
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
24
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
41.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
9
9
0
0
0
0
9
0
0
0
0
34
0
0
% A
% Cys:
0
0
0
17
0
0
0
0
0
0
0
0
34
0
34
% C
% Asp:
0
0
0
9
0
17
0
42
0
0
0
0
0
0
0
% D
% Glu:
9
0
9
9
9
17
34
0
0
9
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
9
0
9
9
9
9
17
0
0
34
0
0
25
% G
% His:
0
0
9
0
0
0
9
0
0
34
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% I
% Lys:
34
67
0
0
17
9
34
17
9
17
34
42
17
9
17
% K
% Leu:
0
0
34
0
0
0
0
0
0
0
0
0
0
9
0
% L
% Met:
0
0
9
0
0
0
0
0
9
0
0
0
0
25
0
% M
% Asn:
9
0
0
25
0
9
0
0
17
34
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
25
0
0
9
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
67
0
9
0
0
% Q
% Arg:
9
17
0
17
25
17
9
0
42
0
0
0
0
17
17
% R
% Ser:
9
0
25
25
42
17
9
9
0
0
0
0
0
9
0
% S
% Thr:
0
0
0
0
0
0
0
17
9
9
0
0
0
17
0
% T
% Val:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _