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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP2U1
All Species:
13.33
Human Site:
S308
Identified Species:
29.33
UniProt:
Q7Z449
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z449
NP_898898.1
544
61987
S308
I
I
K
D
H
Q
E
S
L
D
R
E
N
P
Q
Chimpanzee
Pan troglodytes
Q2XNC8
497
55843
G284
A
E
M
E
K
A
K
G
N
P
E
S
S
F
N
Rhesus Macaque
Macaca mulatta
XP_001084718
394
45585
N181
H
M
E
E
E
R
K
N
N
S
N
S
S
F
D
Dog
Lupus familis
XP_852725
502
57845
N288
Y
L
K
E
M
E
K
N
R
G
N
A
T
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CX98
530
60559
S294
I
I
R
E
H
Q
E
S
L
D
A
S
N
P
Q
Rat
Rattus norvegicus
Q4V8D1
530
60381
S294
I
I
K
E
H
Q
E
S
L
D
A
N
N
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517862
548
61788
S312
L
I
R
E
H
R
E
S
L
D
R
T
A
P
R
Chicken
Gallus gallus
XP_420996
646
71804
E411
K
L
I
E
R
V
S
E
N
R
K
S
Q
S
P
Frog
Xenopus laevis
NP_001085963
502
57933
T287
F
F
E
E
I
E
K
T
K
G
N
P
Q
S
S
Zebra Danio
Brachydanio rerio
NP_001139036
533
60331
D297
A
R
H
R
A
T
L
D
P
E
N
P
R
D
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786956
477
54796
E264
I
K
Q
E
K
I
S
E
A
D
A
S
F
T
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.2
71.3
40.2
N.A.
79
77.7
N.A.
59.8
36.2
39.1
55.1
N.A.
N.A.
N.A.
N.A.
37.5
Protein Similarity:
100
55.7
72
59
N.A.
87.5
86.4
N.A.
71.1
51.5
55.8
71.8
N.A.
N.A.
N.A.
N.A.
58
P-Site Identity:
100
0
0
6.6
N.A.
73.3
80
N.A.
53.3
0
0
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
20
46.6
40
N.A.
86.6
86.6
N.A.
86.6
20
33.3
6.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
0
0
10
10
0
0
10
0
28
10
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
10
0
46
0
0
0
10
10
% D
% Glu:
0
10
19
82
10
19
37
19
0
10
10
10
0
0
10
% E
% Phe:
10
10
0
0
0
0
0
0
0
0
0
0
10
19
10
% F
% Gly:
0
0
0
0
0
0
0
10
0
19
0
0
0
0
0
% G
% His:
10
0
10
0
37
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
37
37
10
0
10
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
10
28
0
19
0
37
0
10
0
10
0
0
0
0
% K
% Leu:
10
19
0
0
0
0
10
0
37
0
0
0
0
0
0
% L
% Met:
0
10
10
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
19
28
0
37
10
28
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
10
10
0
19
0
37
10
% P
% Gln:
0
0
10
0
0
28
0
0
0
0
0
0
19
0
28
% Q
% Arg:
0
10
19
10
10
19
0
0
10
10
19
0
10
0
10
% R
% Ser:
0
0
0
0
0
0
19
37
0
10
0
46
19
28
19
% S
% Thr:
0
0
0
0
0
10
0
10
0
0
0
10
10
10
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _