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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CYP2U1 All Species: 10.61
Human Site: S519 Identified Species: 23.33
UniProt: Q7Z449 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z449 NP_898898.1 544 61987 S519 A F A L P E D S K K P L L T G
Chimpanzee Pan troglodytes Q2XNC8 497 55843 P473 F S V P T G Q P R P S H H G V
Rhesus Macaque Macaca mulatta XP_001084718 394 45585 K370 F A L P K D S K K P L L T G R
Dog Lupus familis XP_852725 502 57845 E477 T F R P P D N E K L S L E F R
Cat Felis silvestris
Mouse Mus musculus Q9CX98 530 60559 S505 T F A L P E G S E K P V M T G
Rat Rattus norvegicus Q4V8D1 530 60381 S505 T F A L P E G S E K P I M T G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517862 548 61788 S523 T F A W P E G S G K P F L Y G
Chicken Gallus gallus XP_420996 646 71804 G621 F H L R F P H G G I P D L K P
Frog Xenopus laevis NP_001085963 502 57933 Q477 E F Q I P T D Q P R P R N D P
Zebra Danio Brachydanio rerio NP_001139036 533 60331 A508 T F R F P E G A T A P S M H G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786956 477 54796 N453 T P A P E N P N P S I Y K N Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 40.2 71.3 40.2 N.A. 79 77.7 N.A. 59.8 36.2 39.1 55.1 N.A. N.A. N.A. N.A. 37.5
Protein Similarity: 100 55.7 72 59 N.A. 87.5 86.4 N.A. 71.1 51.5 55.8 71.8 N.A. N.A. N.A. N.A. 58
P-Site Identity: 100 0 13.3 26.6 N.A. 66.6 66.6 N.A. 60 13.3 26.6 33.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 6.6 20 40 N.A. 86.6 86.6 N.A. 60 13.3 40 46.6 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 46 0 0 0 0 10 0 10 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 19 19 0 0 0 0 10 0 10 0 % D
% Glu: 10 0 0 0 10 46 0 10 19 0 0 0 10 0 0 % E
% Phe: 28 64 0 10 10 0 0 0 0 0 0 10 0 10 0 % F
% Gly: 0 0 0 0 0 10 37 10 19 0 0 0 0 19 46 % G
% His: 0 10 0 0 0 0 10 0 0 0 0 10 10 10 0 % H
% Ile: 0 0 0 10 0 0 0 0 0 10 10 10 0 0 0 % I
% Lys: 0 0 0 0 10 0 0 10 28 37 0 0 10 10 0 % K
% Leu: 0 0 19 28 0 0 0 0 0 10 10 28 28 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 28 0 0 % M
% Asn: 0 0 0 0 0 10 10 10 0 0 0 0 10 10 0 % N
% Pro: 0 10 0 37 64 10 10 10 19 19 64 0 0 0 19 % P
% Gln: 0 0 10 0 0 0 10 10 0 0 0 0 0 0 0 % Q
% Arg: 0 0 19 10 0 0 0 0 10 10 0 10 0 0 19 % R
% Ser: 0 10 0 0 0 0 10 37 0 10 19 10 0 0 0 % S
% Thr: 55 0 0 0 10 10 0 0 10 0 0 0 10 28 0 % T
% Val: 0 0 10 0 0 0 0 0 0 0 0 10 0 0 10 % V
% Trp: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 10 0 10 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _