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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CYP2U1 All Species: 0.91
Human Site: S85 Identified Species: 2
UniProt: Q7Z449 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z449 NP_898898.1 544 61987 S85 P P F L R R R S W L S S R T R
Chimpanzee Pan troglodytes Q2XNC8 497 55843 F65 F D Q L R R R F G D V F S L Q
Rhesus Macaque Macaca mulatta XP_001084718 394 45585
Dog Lupus familis XP_852725 502 57845 K67 D F E Q S H L K L Q R F V K K
Cat Felis silvestris
Mouse Mus musculus Q9CX98 530 60559 F71 G H L L V P R F L R P Q F W L
Rat Rattus norvegicus Q4V8D1 530 60381 F71 G Y L L L P R F L R L H F W L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517862 548 61788 G89 V C G N R P R G A K S S A Q Q
Chicken Gallus gallus XP_420996 646 71804 G189 R P P G F P P G P A G L P L I
Frog Xenopus laevis NP_001085963 502 57933 S68 K D I P T S L S K L R K R Y G
Zebra Danio Brachydanio rerio NP_001139036 533 60331 R68 V P P F I L K R F V K N S K E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786956 477 54796 M44 P H L T L M D M A K K Y G N V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 40.2 71.3 40.2 N.A. 79 77.7 N.A. 59.8 36.2 39.1 55.1 N.A. N.A. N.A. N.A. 37.5
Protein Similarity: 100 55.7 72 59 N.A. 87.5 86.4 N.A. 71.1 51.5 55.8 71.8 N.A. N.A. N.A. N.A. 58
P-Site Identity: 100 26.6 0 0 N.A. 13.3 13.3 N.A. 26.6 6.6 20 6.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 33.3 0 6.6 N.A. 13.3 13.3 N.A. 33.3 6.6 20 33.3 N.A. N.A. N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 19 10 0 0 10 0 0 % A
% Cys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 19 0 0 0 0 10 0 0 10 0 0 0 0 0 % D
% Glu: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 10 % E
% Phe: 10 10 10 10 10 0 0 28 10 0 0 19 19 0 0 % F
% Gly: 19 0 10 10 0 0 0 19 10 0 10 0 10 0 10 % G
% His: 0 19 0 0 0 10 0 0 0 0 0 10 0 0 0 % H
% Ile: 0 0 10 0 10 0 0 0 0 0 0 0 0 0 10 % I
% Lys: 10 0 0 0 0 0 10 10 10 19 19 10 0 19 10 % K
% Leu: 0 0 28 37 19 10 19 0 28 19 10 10 0 19 19 % L
% Met: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 0 0 0 0 10 0 10 0 % N
% Pro: 19 28 19 10 0 37 10 0 10 0 10 0 10 0 0 % P
% Gln: 0 0 10 10 0 0 0 0 0 10 0 10 0 10 19 % Q
% Arg: 10 0 0 0 28 19 46 10 0 19 19 0 19 0 10 % R
% Ser: 0 0 0 0 10 10 0 19 0 0 19 19 19 0 0 % S
% Thr: 0 0 0 10 10 0 0 0 0 0 0 0 0 10 0 % T
% Val: 19 0 0 0 10 0 0 0 0 10 10 0 10 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 10 0 0 0 0 19 0 % W
% Tyr: 0 10 0 0 0 0 0 0 0 0 0 10 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _