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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP2U1
All Species:
14.55
Human Site:
Y321
Identified Species:
32
UniProt:
Q7Z449
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z449
NP_898898.1
544
61987
Y321
P
Q
D
F
I
D
M
Y
L
L
H
M
E
E
E
Chimpanzee
Pan troglodytes
Q2XNC8
497
55843
I297
F
N
D
E
N
L
R
I
V
V
A
D
L
F
S
Rhesus Macaque
Macaca mulatta
XP_001084718
394
45585
Y194
F
D
E
E
Y
L
F
Y
I
I
G
D
L
F
I
Dog
Lupus familis
XP_852725
502
57845
L301
S
S
F
H
E
E
N
L
I
Y
S
T
L
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9CX98
530
60559
Y307
P
Q
D
F
I
D
M
Y
L
L
H
M
E
E
E
Rat
Rattus norvegicus
Q4V8D1
530
60381
Y307
P
Q
D
F
I
D
M
Y
L
L
H
T
Q
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517862
548
61788
Y325
P
R
D
F
I
D
M
Y
L
L
H
M
E
E
E
Chicken
Gallus gallus
XP_420996
646
71804
A424
S
P
R
H
F
I
D
A
Y
L
D
E
M
D
C
Frog
Xenopus laevis
NP_001085963
502
57933
L300
S
S
F
N
E
T
A
L
L
Y
T
I
A
D
L
Zebra Danio
Brachydanio rerio
NP_001139036
533
60331
V310
D
F
I
D
M
Y
L
V
E
M
L
A
K
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786956
477
54796
I277
T
E
T
Y
L
F
H
I
L
N
D
L
I
F
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.2
71.3
40.2
N.A.
79
77.7
N.A.
59.8
36.2
39.1
55.1
N.A.
N.A.
N.A.
N.A.
37.5
Protein Similarity:
100
55.7
72
59
N.A.
87.5
86.4
N.A.
71.1
51.5
55.8
71.8
N.A.
N.A.
N.A.
N.A.
58
P-Site Identity:
100
6.6
6.6
0
N.A.
100
86.6
N.A.
93.3
6.6
6.6
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
20
26.6
20
N.A.
100
93.3
N.A.
100
13.3
20
40
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
10
0
0
10
10
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
10
10
46
10
0
37
10
0
0
0
19
19
0
28
0
% D
% Glu:
0
10
10
19
19
10
0
0
10
0
0
10
28
37
37
% E
% Phe:
19
10
19
37
10
10
10
0
0
0
0
0
0
28
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% G
% His:
0
0
0
19
0
0
10
0
0
0
37
0
0
0
0
% H
% Ile:
0
0
10
0
37
10
0
19
19
10
0
10
10
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% K
% Leu:
0
0
0
0
10
19
10
19
55
46
10
10
28
0
19
% L
% Met:
0
0
0
0
10
0
37
0
0
10
0
28
10
0
0
% M
% Asn:
0
10
0
10
10
0
10
0
0
10
0
0
0
0
0
% N
% Pro:
37
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
28
0
0
0
0
0
0
0
0
0
0
10
10
0
% Q
% Arg:
0
10
10
0
0
0
10
0
0
0
0
0
0
0
0
% R
% Ser:
28
19
0
0
0
0
0
0
0
0
10
0
0
0
10
% S
% Thr:
10
0
10
0
0
10
0
0
0
0
10
19
0
0
0
% T
% Val:
0
0
0
0
0
0
0
10
10
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
10
10
0
46
10
19
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _