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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NPHP3 All Species: 22.73
Human Site: S785 Identified Species: 55.56
UniProt: Q7Z494 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z494 NP_694972.3 1330 150864 S785 S H N G V S E S E L M E L Y P
Chimpanzee Pan troglodytes XP_516758 2073 234018 S798 S H N G V S E S E L M E L Y P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_863943 2040 230770 S765 S H N G M N E S E L M E L Y P
Cat Felis silvestris
Mouse Mus musculus Q7TNH6 1324 150168 S780 S H N G V S E S E L M E L Y P
Rat Rattus norvegicus XP_343462 1325 150597 S781 S H N G V S E S E L M E L Y P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514031 1275 145541 E729 H N G V S E S E L M E L Y P E
Chicken Gallus gallus XP_418790 1315 149161 E770 H N G V S E S E L M E L Y P E
Frog Xenopus laevis Q6AZT7 1300 148301 E758 H N G V S E C E L M E L C P G
Zebra Danio Brachydanio rerio XP_691073 1303 148244 S763 S H N G I S E S E V L E L F P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001203493 1012 113472 P476 V G A A G P L P P L L V S G V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 61.7 N.A. 61.5 N.A. 88.8 87.9 N.A. 78 83.9 76.9 69.9 N.A. N.A. N.A. N.A. 30.9
Protein Similarity: 100 62.4 N.A. 63 N.A. 93.3 93.3 N.A. 86.2 90.7 86.5 82.9 N.A. N.A. N.A. N.A. 49.1
P-Site Identity: 100 100 N.A. 86.6 N.A. 100 100 N.A. 0 0 0 73.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 13.3 13.3 13.3 100 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 10 0 0 0 0 0 10 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 30 60 30 60 0 30 60 0 0 20 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % F
% Gly: 0 10 30 60 10 0 0 0 0 0 0 0 0 10 10 % G
% His: 30 60 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 10 0 30 60 20 30 60 0 0 % L
% Met: 0 0 0 0 10 0 0 0 0 30 50 0 0 0 0 % M
% Asn: 0 30 60 0 0 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 10 0 10 10 0 0 0 0 30 60 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 60 0 0 0 30 50 20 60 0 0 0 0 10 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 10 0 0 30 40 0 0 0 0 10 0 10 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 20 50 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _