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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPHP3
All Species:
34.55
Human Site:
T666
Identified Species:
84.44
UniProt:
Q7Z494
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z494
NP_694972.3
1330
150864
T666
P
A
W
R
L
W
P
T
L
H
L
D
P
L
S
Chimpanzee
Pan troglodytes
XP_516758
2073
234018
T679
P
A
W
R
L
W
P
T
L
H
L
D
P
L
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_863943
2040
230770
T646
P
A
W
R
L
W
P
T
L
H
L
D
P
L
N
Cat
Felis silvestris
Mouse
Mus musculus
Q7TNH6
1324
150168
T662
T
A
W
R
L
W
P
T
L
H
L
D
P
L
S
Rat
Rattus norvegicus
XP_343462
1325
150597
T662
T
A
W
R
L
W
P
T
L
H
L
D
P
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514031
1275
145541
T609
Q
A
W
R
L
W
P
T
L
H
L
D
P
L
N
Chicken
Gallus gallus
XP_418790
1315
149161
T650
Q
A
W
R
L
W
P
T
L
H
L
D
P
L
N
Frog
Xenopus laevis
Q6AZT7
1300
148301
T638
Q
A
W
R
L
W
P
T
L
H
L
D
P
L
N
Zebra Danio
Brachydanio rerio
XP_691073
1303
148244
T644
Q
A
W
R
L
W
P
T
L
H
L
D
P
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203493
1012
113472
K375
I
K
N
S
G
N
A
K
I
L
E
G
L
E
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.7
N.A.
61.5
N.A.
88.8
87.9
N.A.
78
83.9
76.9
69.9
N.A.
N.A.
N.A.
N.A.
30.9
Protein Similarity:
100
62.4
N.A.
63
N.A.
93.3
93.3
N.A.
86.2
90.7
86.5
82.9
N.A.
N.A.
N.A.
N.A.
49.1
P-Site Identity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
86.6
86.6
86.6
86.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
93.3
93.3
93.3
93.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
90
0
0
0
0
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
90
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
90
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
90
0
0
0
90
10
90
0
10
90
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
50
% N
% Pro:
30
0
0
0
0
0
90
0
0
0
0
0
90
0
0
% P
% Gln:
40
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
90
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
50
% S
% Thr:
20
0
0
0
0
0
0
90
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
90
0
0
90
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _