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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HDDC2
All Species:
0
Human Site:
S192
Identified Species:
0
UniProt:
Q7Z4H3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z4H3
NP_057147.2
204
23390
S192
S
E
L
E
A
E
R
S
T
N
I
A
A
A
A
Chimpanzee
Pan troglodytes
XP_001152848
282
31963
W256
S
K
K
C
D
T
T
W
A
L
K
E
A
T
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533487
207
23510
N195
S
E
L
E
A
E
R
N
A
S
I
A
A
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q3SXD3
199
22734
N187
S
E
L
E
T
E
R
N
A
S
M
A
T
A
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507226
188
21731
N174
S
E
L
M
T
E
R
N
S
R
M
A
A
A
T
Chicken
Gallus gallus
Frog
Xenopus laevis
Q66L17
201
23091
N189
S
A
I
Y
E
E
R
N
S
A
I
A
E
N
A
Zebra Danio
Brachydanio rerio
Q1LUI2
200
22901
A179
K
S
L
N
E
E
R
A
R
H
I
A
A
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609052
388
42501
D355
N
E
I
Y
E
Q
R
D
V
L
A
K
A
K
G
Honey Bee
Apis mellifera
XP_624893
190
21983
R179
A
S
E
I
I
A
R
R
Q
A
L
C
C
N
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002309375
207
23067
A196
T
E
V
G
K
A
W
A
L
E
I
A
S
R
R
Maize
Zea mays
NP_001148228
246
26685
K210
L
Q
A
L
E
Y
E
K
E
Q
G
R
D
L
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_973522
257
28363
A246
T
N
I
G
K
A
W
A
S
E
I
V
S
R
R
Baker's Yeast
Sacchar. cerevisiae
P38331
238
27558
Q226
S
D
L
V
V
Q
R
Q
K
Y
F
A
D
L
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.7
N.A.
79.2
N.A.
86.7
N.A.
N.A.
71.5
N.A.
71
62.2
N.A.
27.5
41.6
N.A.
N.A.
Protein Similarity:
100
65.2
N.A.
86.9
N.A.
93.6
N.A.
N.A.
83.8
N.A.
85.7
78.9
N.A.
38.9
65.1
N.A.
N.A.
P-Site Identity:
100
13.3
N.A.
80
N.A.
53.3
N.A.
N.A.
53.3
N.A.
40
40
N.A.
20
6.6
N.A.
N.A.
P-Site Similarity:
100
20
N.A.
93.3
N.A.
80
N.A.
N.A.
73.3
N.A.
60
53.3
N.A.
40
20
N.A.
N.A.
Percent
Protein Identity:
44.9
42.6
N.A.
37.7
36.9
N.A.
Protein Similarity:
63.7
55.6
N.A.
53.7
54.6
N.A.
P-Site Identity:
20
0
N.A.
6.6
26.6
N.A.
P-Site Similarity:
46.6
6.6
N.A.
40
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
16
24
0
24
24
16
8
62
47
31
24
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
8
8
0
0
% C
% Asp:
0
8
0
0
8
0
0
8
0
0
0
0
16
0
0
% D
% Glu:
0
47
8
24
31
47
8
0
8
16
0
8
8
0
16
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
16
0
0
0
0
0
0
8
0
0
8
16
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
24
8
8
0
0
0
0
0
47
0
0
0
0
% I
% Lys:
8
8
8
0
16
0
0
8
8
0
8
8
0
8
0
% K
% Leu:
8
0
47
8
0
0
0
0
8
16
8
0
0
16
8
% L
% Met:
0
0
0
8
0
0
0
0
0
0
16
0
0
0
0
% M
% Asn:
8
8
0
8
0
0
0
31
0
8
0
0
0
16
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
16
0
8
8
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
70
8
8
8
0
8
0
16
16
% R
% Ser:
54
16
0
0
0
0
0
8
24
16
0
0
16
0
8
% S
% Thr:
16
0
0
0
16
8
8
0
8
0
0
0
8
8
16
% T
% Val:
0
0
8
8
8
0
0
0
8
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
16
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
16
0
8
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _