KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HDDC2
All Species:
27.88
Human Site:
S45
Identified Species:
51.11
UniProt:
Q7Z4H3
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z4H3
NP_057147.2
204
23390
S45
R
N
V
Q
R
P
E
S
V
S
D
H
M
Y
R
Chimpanzee
Pan troglodytes
XP_001152848
282
31963
S109
R
N
V
Q
R
P
E
S
V
S
D
H
M
Y
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533487
207
23510
S48
R
S
V
E
R
P
E
S
V
S
D
H
M
Y
R
Cat
Felis silvestris
Mouse
Mus musculus
Q3SXD3
199
22734
D63
R
D
D
R
L
N
K
D
R
C
I
R
L
A
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507226
188
21731
A70
E
C
I
V
G
D
I
A
P
A
D
N
V
P
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Q66L17
201
23091
V52
D
H
M
Y
R
M
A
V
M
A
M
L
T
E
D
Zebra Danio
Brachydanio rerio
Q1LUI2
200
22901
E55
Q
D
I
S
V
N
K
E
R
C
M
K
L
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609052
388
42501
S208
R
D
V
N
D
C
E
S
I
S
G
H
M
Y
R
Honey Bee
Apis mellifera
XP_624893
190
21983
V57
D
N
E
N
L
D
K
V
K
I
M
Q
M
A
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002309375
207
23067
S57
R
G
I
K
G
P
E
S
I
S
D
H
M
Y
R
Maize
Zea mays
NP_001148228
246
26685
S97
R
G
V
Q
A
P
E
S
V
A
D
H
M
Y
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_973522
257
28363
S107
R
D
V
K
D
P
E
S
I
A
D
H
M
Y
R
Baker's Yeast
Sacchar. cerevisiae
P38331
238
27558
S76
L
G
I
K
E
C
E
S
I
S
D
H
M
Y
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.7
N.A.
79.2
N.A.
86.7
N.A.
N.A.
71.5
N.A.
71
62.2
N.A.
27.5
41.6
N.A.
N.A.
Protein Similarity:
100
65.2
N.A.
86.9
N.A.
93.6
N.A.
N.A.
83.8
N.A.
85.7
78.9
N.A.
38.9
65.1
N.A.
N.A.
P-Site Identity:
100
100
N.A.
86.6
N.A.
6.6
N.A.
N.A.
6.6
N.A.
6.6
0
N.A.
60
13.3
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
33.3
N.A.
N.A.
46.6
N.A.
33.3
33.3
N.A.
73.3
20
N.A.
N.A.
Percent
Protein Identity:
44.9
42.6
N.A.
37.7
36.9
N.A.
Protein Similarity:
63.7
55.6
N.A.
53.7
54.6
N.A.
P-Site Identity:
66.6
80
N.A.
66.6
53.3
N.A.
P-Site Similarity:
86.6
86.6
N.A.
93.3
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
8
8
0
31
0
0
0
24
0
% A
% Cys:
0
8
0
0
0
16
0
0
0
16
0
0
0
0
0
% C
% Asp:
16
31
8
0
16
16
0
8
0
0
62
0
0
0
8
% D
% Glu:
8
0
8
8
8
0
62
8
0
0
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
24
0
0
16
0
0
0
0
0
8
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
62
0
0
0
% H
% Ile:
0
0
31
0
0
0
8
0
31
8
8
0
0
0
0
% I
% Lys:
0
0
0
24
0
0
24
0
8
0
0
8
0
0
8
% K
% Leu:
8
0
0
0
16
0
0
0
0
0
0
8
16
0
24
% L
% Met:
0
0
8
0
0
8
0
0
8
0
24
0
70
0
0
% M
% Asn:
0
24
0
16
0
16
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
47
0
0
8
0
0
0
0
8
0
% P
% Gln:
8
0
0
24
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
62
0
0
8
31
0
0
0
16
0
0
8
0
0
62
% R
% Ser:
0
8
0
8
0
0
0
62
0
47
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% T
% Val:
0
0
47
8
8
0
0
16
31
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
62
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _