KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HDDC2
All Species:
13.96
Human Site:
S6
Identified Species:
25.6
UniProt:
Q7Z4H3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z4H3
NP_057147.2
204
23390
S6
_
_
M
A
S
V
S
S
A
T
F
S
G
H
G
Chimpanzee
Pan troglodytes
XP_001152848
282
31963
S70
G
R
M
A
S
V
S
S
A
T
F
S
G
H
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533487
207
23510
N8
M
P
P
P
L
C
D
N
Q
K
K
S
P
N
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3SXD3
199
22734
S8
M
A
L
A
S
S
G
S
G
A
G
L
L
R
F
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507226
188
21731
R11
C
E
R
G
P
G
K
R
V
P
R
T
G
W
V
Chicken
Gallus gallus
Frog
Xenopus laevis
Q66L17
201
23091
S6
_
_
M
A
A
A
G
S
C
S
S
A
G
K
S
Zebra Danio
Brachydanio rerio
Q1LUI2
200
22901
R16
K
L
V
G
Q
L
K
R
V
P
R
T
G
W
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609052
388
42501
S166
E
V
A
A
A
S
A
S
A
G
K
K
P
C
F
Honey Bee
Apis mellifera
XP_624893
190
21983
H18
E
L
V
G
R
L
K
H
M
K
R
T
G
W
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002309375
207
23067
A18
S
L
T
T
N
D
T
A
S
P
S
P
S
P
S
Maize
Zea mays
NP_001148228
246
26685
S46
H
R
L
A
A
A
M
S
S
S
S
S
P
T
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_973522
257
28363
S69
P
N
V
A
A
V
P
S
S
S
S
S
S
S
A
Baker's Yeast
Sacchar. cerevisiae
P38331
238
27558
R21
S
V
E
A
G
K
T
R
L
T
T
E
W
K
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.7
N.A.
79.2
N.A.
86.7
N.A.
N.A.
71.5
N.A.
71
62.2
N.A.
27.5
41.6
N.A.
N.A.
Protein Similarity:
100
65.2
N.A.
86.9
N.A.
93.6
N.A.
N.A.
83.8
N.A.
85.7
78.9
N.A.
38.9
65.1
N.A.
N.A.
P-Site Identity:
100
86.6
N.A.
6.6
N.A.
20
N.A.
N.A.
6.6
N.A.
30.7
6.6
N.A.
20
6.6
N.A.
N.A.
P-Site Similarity:
100
93.3
N.A.
20
N.A.
26.6
N.A.
N.A.
13.3
N.A.
53.8
26.6
N.A.
33.3
26.6
N.A.
N.A.
Percent
Protein Identity:
44.9
42.6
N.A.
37.7
36.9
N.A.
Protein Similarity:
63.7
55.6
N.A.
53.7
54.6
N.A.
P-Site Identity:
0
20
N.A.
26.6
13.3
N.A.
P-Site Similarity:
26.6
46.6
N.A.
53.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
62
31
16
8
8
24
8
0
8
0
0
8
% A
% Cys:
8
0
0
0
0
8
0
0
8
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% D
% Glu:
16
8
8
0
0
0
0
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
16
% F
% Gly:
8
0
0
24
8
8
16
0
8
8
8
0
47
0
16
% G
% His:
8
0
0
0
0
0
0
8
0
0
0
0
0
16
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
0
0
8
24
0
0
16
16
8
0
16
0
% K
% Leu:
0
24
16
0
8
16
0
0
8
0
0
8
8
0
8
% L
% Met:
16
0
24
0
0
0
8
0
8
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
8
0
0
8
0
0
0
0
0
8
0
% N
% Pro:
8
8
8
8
8
0
8
0
0
24
0
8
24
8
16
% P
% Gln:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
16
8
0
8
0
0
24
0
0
24
0
0
8
0
% R
% Ser:
16
0
0
0
24
16
16
54
24
24
31
39
16
8
16
% S
% Thr:
0
0
8
8
0
0
16
0
0
24
8
24
0
8
0
% T
% Val:
0
16
24
0
0
24
0
0
16
0
0
0
0
0
24
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
24
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
16
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% _