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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRIM46 All Species: 20.3
Human Site: S500 Identified Species: 44.67
UniProt: Q7Z4K8 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z4K8 NP_079334.3 759 83424 S500 L E N P D T G S V Y V L R V R
Chimpanzee Pan troglodytes XP_001153443 644 71824 T393 H N R I A R A T E A L Q T F R
Rhesus Macaque Macaca mulatta XP_001115341 759 83345 S500 L E N P D T G S V Y V L R V R
Dog Lupus familis XP_547551 806 88215 S500 L E N P D T G S V Y V L R V R
Cat Felis silvestris
Mouse Mus musculus Q7TNM2 759 83413 S500 L E N P D T G S V Y V L R V R
Rat Rattus norvegicus P82458 667 75192 Q417 S V V S Y E L Q Y T I F T G Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507426 727 82010 I474 V Y G T T K V I S D L E N N S
Chicken Gallus gallus XP_424421 1176 130133 S924 I S D L D D D S S Y A F R V R
Frog Xenopus laevis NP_001084586 733 82647 L483 T S K I L T D L D L N S Q Y C
Zebra Danio Brachydanio rerio XP_698412 751 83510 S493 I D K L E M D S V Y V L R V R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001193303 888 97429 E603 S N R C T C L E W T P S A D G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.1 99.7 92.8 N.A. 97.8 25.6 N.A. 41.6 29.4 43.2 57.7 N.A. N.A. N.A. N.A. 23.3
Protein Similarity: 100 84.4 99.7 93.1 N.A. 98.9 42 N.A. 59.9 41.8 62.1 72.9 N.A. N.A. N.A. N.A. 39.3
P-Site Identity: 100 6.6 100 100 N.A. 100 0 N.A. 0 40 6.6 53.3 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 20 100 100 N.A. 100 13.3 N.A. 13.3 53.3 13.3 73.3 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 10 0 0 10 10 0 10 0 0 % A
% Cys: 0 0 0 10 0 10 0 0 0 0 0 0 0 0 10 % C
% Asp: 0 10 10 0 46 10 28 0 10 10 0 0 0 10 0 % D
% Glu: 0 37 0 0 10 10 0 10 10 0 0 10 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 19 0 10 0 % F
% Gly: 0 0 10 0 0 0 37 0 0 0 0 0 0 10 10 % G
% His: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 19 0 0 19 0 0 0 10 0 0 10 0 0 0 0 % I
% Lys: 0 0 19 0 0 10 0 0 0 0 0 0 0 0 0 % K
% Leu: 37 0 0 19 10 0 19 10 0 10 19 46 0 0 0 % L
% Met: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 19 37 0 0 0 0 0 0 0 10 0 10 10 0 % N
% Pro: 0 0 0 37 0 0 0 0 0 0 10 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 10 0 0 0 10 10 0 10 % Q
% Arg: 0 0 19 0 0 10 0 0 0 0 0 0 55 0 64 % R
% Ser: 19 19 0 10 0 0 0 55 19 0 0 19 0 0 10 % S
% Thr: 10 0 0 10 19 46 0 10 0 19 0 0 19 0 0 % T
% Val: 10 10 10 0 0 0 10 0 46 0 46 0 0 55 0 % V
% Trp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 10 0 0 0 10 55 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _