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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRIM46 All Species: 21.82
Human Site: S518 Identified Species: 48
UniProt: Q7Z4K8 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z4K8 NP_079334.3 759 83424 S518 K A G Y G E Y S E D V H L H T
Chimpanzee Pan troglodytes XP_001153443 644 71824 Q411 S S S F R H C Q L D V G R E M
Rhesus Macaque Macaca mulatta XP_001115341 759 83345 S518 K A G Y G E Y S E D V H L H T
Dog Lupus familis XP_547551 806 88215 S518 K A G Y G E Y S E D V H L H T
Cat Felis silvestris
Mouse Mus musculus Q7TNM2 759 83413 S518 K A G Y G E Y S E D V H L H T
Rat Rattus norvegicus P82458 667 75192 D435 V S L C N S A D S W M I V P N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507426 727 82010 G492 F R V R G Y K G A S C S P C S
Chicken Gallus gallus XP_424421 1176 130133 S942 G S I C S S W S K E V I L R T
Frog Xenopus laevis NP_001084586 733 82647 S501 K G Y R G S T S T P L S K E V
Zebra Danio Brachydanio rerio XP_698412 751 83510 S511 K A G F G E Y S E E V Y L H T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001193303 888 97429 I621 A S Y S L E Y I K L D P K Q T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.1 99.7 92.8 N.A. 97.8 25.6 N.A. 41.6 29.4 43.2 57.7 N.A. N.A. N.A. N.A. 23.3
Protein Similarity: 100 84.4 99.7 93.1 N.A. 98.9 42 N.A. 59.9 41.8 62.1 72.9 N.A. N.A. N.A. N.A. 39.3
P-Site Identity: 100 13.3 100 100 N.A. 100 0 N.A. 6.6 26.6 20 80 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 26.6 100 100 N.A. 100 20 N.A. 13.3 53.3 26.6 100 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 46 0 0 0 0 10 0 10 0 0 0 0 0 0 % A
% Cys: 0 0 0 19 0 0 10 0 0 0 10 0 0 10 0 % C
% Asp: 0 0 0 0 0 0 0 10 0 46 10 0 0 0 0 % D
% Glu: 0 0 0 0 0 55 0 0 46 19 0 0 0 19 0 % E
% Phe: 10 0 0 19 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 10 46 0 64 0 0 10 0 0 0 10 0 0 0 % G
% His: 0 0 0 0 0 10 0 0 0 0 0 37 0 46 0 % H
% Ile: 0 0 10 0 0 0 0 10 0 0 0 19 0 0 0 % I
% Lys: 55 0 0 0 0 0 10 0 19 0 0 0 19 0 0 % K
% Leu: 0 0 10 0 10 0 0 0 10 10 10 0 55 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 10 % M
% Asn: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 10 % N
% Pro: 0 0 0 0 0 0 0 0 0 10 0 10 10 10 0 % P
% Gln: 0 0 0 0 0 0 0 10 0 0 0 0 0 10 0 % Q
% Arg: 0 10 0 19 10 0 0 0 0 0 0 0 10 10 0 % R
% Ser: 10 37 10 10 10 28 0 64 10 10 0 19 0 0 10 % S
% Thr: 0 0 0 0 0 0 10 0 10 0 0 0 0 0 64 % T
% Val: 10 0 10 0 0 0 0 0 0 0 64 0 10 0 10 % V
% Trp: 0 0 0 0 0 0 10 0 0 10 0 0 0 0 0 % W
% Tyr: 0 0 19 37 0 10 55 0 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _