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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRIM46
All Species:
14.85
Human Site:
S618
Identified Species:
32.67
UniProt:
Q7Z4K8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z4K8
NP_079334.3
759
83424
S618
L
E
S
K
L
Q
E
S
F
Q
G
A
P
D
V
Chimpanzee
Pan troglodytes
XP_001153443
644
71824
K511
L
R
V
R
G
C
N
K
A
G
Y
G
E
Y
S
Rhesus Macaque
Macaca mulatta
XP_001115341
759
83345
S618
L
E
S
K
L
Q
E
S
F
Q
G
A
P
D
V
Dog
Lupus familis
XP_547551
806
88215
S618
L
E
S
K
L
Q
E
S
F
Q
G
A
P
D
V
Cat
Felis silvestris
Mouse
Mus musculus
Q7TNM2
759
83413
S618
L
E
S
K
L
Q
E
S
F
Q
G
A
P
D
V
Rat
Rattus norvegicus
P82458
667
75192
F535
Y
G
V
A
G
N
V
F
I
D
S
G
R
H
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507426
727
82010
A592
L
V
K
V
G
V
V
A
D
S
K
L
Q
E
W
Chicken
Gallus gallus
XP_424421
1176
130133
F1042
S
S
T
K
I
Q
K
F
F
H
N
T
H
D
V
Frog
Xenopus laevis
NP_001084586
733
82647
K601
V
G
V
A
S
D
I
K
L
Q
E
W
L
Y
N
Zebra Danio
Brachydanio rerio
XP_698412
751
83510
W611
V
E
A
K
L
Q
E
W
F
H
L
P
Q
D
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193303
888
97429
T721
C
Q
S
S
V
A
H
T
S
S
K
I
R
K
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.1
99.7
92.8
N.A.
97.8
25.6
N.A.
41.6
29.4
43.2
57.7
N.A.
N.A.
N.A.
N.A.
23.3
Protein Similarity:
100
84.4
99.7
93.1
N.A.
98.9
42
N.A.
59.9
41.8
62.1
72.9
N.A.
N.A.
N.A.
N.A.
39.3
P-Site Identity:
100
6.6
100
100
N.A.
100
0
N.A.
6.6
33.3
6.6
46.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
13.3
100
100
N.A.
100
0
N.A.
20
53.3
13.3
66.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
19
0
10
0
10
10
0
0
37
0
0
0
% A
% Cys:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
10
10
0
0
0
55
10
% D
% Glu:
0
46
0
0
0
0
46
0
0
0
10
0
10
10
0
% E
% Phe:
0
0
0
0
0
0
0
19
55
0
0
0
0
0
0
% F
% Gly:
0
19
0
0
28
0
0
0
0
10
37
19
0
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
19
0
0
10
10
0
% H
% Ile:
0
0
0
0
10
0
10
0
10
0
0
10
0
0
0
% I
% Lys:
0
0
10
55
0
0
10
19
0
0
19
0
0
10
0
% K
% Leu:
55
0
0
0
46
0
0
0
10
0
10
10
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
10
10
0
0
0
10
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
10
37
0
0
% P
% Gln:
0
10
0
0
0
55
0
0
0
46
0
0
19
0
0
% Q
% Arg:
0
10
0
10
0
0
0
0
0
0
0
0
19
0
0
% R
% Ser:
10
10
46
10
10
0
0
37
10
19
10
0
0
0
10
% S
% Thr:
0
0
10
0
0
0
0
10
0
0
0
10
0
0
0
% T
% Val:
19
10
28
10
10
10
19
0
0
0
0
0
0
0
46
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
10
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
10
0
0
19
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _