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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRIM46
All Species:
15.76
Human Site:
T398
Identified Species:
34.67
UniProt:
Q7Z4K8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z4K8
NP_079334.3
759
83424
T398
R
A
T
E
A
L
Q
T
F
R
P
A
A
S
S
Chimpanzee
Pan troglodytes
XP_001153443
644
71824
I292
Q
D
T
V
Q
T
Q
I
C
E
L
E
E
A
V
Rhesus Macaque
Macaca mulatta
XP_001115341
759
83345
T398
R
A
T
E
A
L
Q
T
F
R
P
A
A
S
S
Dog
Lupus familis
XP_547551
806
88215
T398
R
A
T
E
A
L
Q
T
F
R
P
A
A
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q7TNM2
759
83413
T398
R
A
T
E
A
L
Q
T
F
R
P
A
A
S
S
Rat
Rattus norvegicus
P82458
667
75192
A316
S
A
S
L
I
S
Q
A
E
H
S
L
K
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507426
727
82010
Q373
K
Q
L
H
V
R
I
Q
N
A
T
E
S
L
K
Chicken
Gallus gallus
XP_424421
1176
130133
S821
R
I
Q
K
A
T
E
S
L
K
S
F
R
P
A
Frog
Xenopus laevis
NP_001084586
733
82647
R382
Q
L
H
I
R
I
Q
R
A
S
E
S
L
T
S
Zebra Danio
Brachydanio rerio
XP_698412
751
83510
H376
K
A
I
E
N
L
Q
H
F
S
L
S
A
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193303
888
97429
K502
R
R
T
Q
N
I
R
K
V
L
D
T
Y
K
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.1
99.7
92.8
N.A.
97.8
25.6
N.A.
41.6
29.4
43.2
57.7
N.A.
N.A.
N.A.
N.A.
23.3
Protein Similarity:
100
84.4
99.7
93.1
N.A.
98.9
42
N.A.
59.9
41.8
62.1
72.9
N.A.
N.A.
N.A.
N.A.
39.3
P-Site Identity:
100
13.3
100
100
N.A.
100
13.3
N.A.
0
13.3
13.3
40
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
26.6
100
100
N.A.
100
26.6
N.A.
13.3
46.6
40
53.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
55
0
0
46
0
0
10
10
10
0
37
46
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
10
0
0
10
0
% D
% Glu:
0
0
0
46
0
0
10
0
10
10
10
19
10
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
46
0
0
10
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
10
10
0
0
0
10
0
10
0
0
0
0
0
% H
% Ile:
0
10
10
10
10
19
10
10
0
0
0
0
0
0
0
% I
% Lys:
19
0
0
10
0
0
0
10
0
10
0
0
10
10
10
% K
% Leu:
0
10
10
10
0
46
0
0
10
10
19
10
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
19
0
0
0
10
0
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
37
0
0
10
10
% P
% Gln:
19
10
10
10
10
0
73
10
0
0
0
0
0
0
0
% Q
% Arg:
55
10
0
0
10
10
10
10
0
37
0
0
10
0
0
% R
% Ser:
10
0
10
0
0
10
0
10
0
19
19
19
10
37
46
% S
% Thr:
0
0
55
0
0
19
0
37
0
0
10
10
0
10
0
% T
% Val:
0
0
0
10
10
0
0
0
10
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _