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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRIM46
All Species:
18.48
Human Site:
T489
Identified Species:
40.67
UniProt:
Q7Z4K8
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z4K8
NP_079334.3
759
83424
T489
R
R
E
E
V
R
G
T
S
A
L
L
E
N
P
Chimpanzee
Pan troglodytes
XP_001153443
644
71824
A382
Q
P
C
F
V
Q
A
A
K
Q
L
H
N
R
I
Rhesus Macaque
Macaca mulatta
XP_001115341
759
83345
T489
R
R
E
E
V
R
G
T
S
A
L
L
E
N
P
Dog
Lupus familis
XP_547551
806
88215
T489
R
R
E
E
V
R
G
T
S
A
L
L
E
N
P
Cat
Felis silvestris
Mouse
Mus musculus
Q7TNM2
759
83413
T489
R
R
E
E
V
R
G
T
S
A
L
L
E
N
P
Rat
Rattus norvegicus
P82458
667
75192
D406
I
T
V
H
W
T
S
D
D
E
F
S
V
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507426
727
82010
T463
M
G
D
S
L
A
W
T
E
S
G
V
Y
G
T
Chicken
Gallus gallus
XP_424421
1176
130133
K913
Q
E
A
E
V
Y
S
K
S
K
V
I
S
D
L
Frog
Xenopus laevis
NP_001084586
733
82647
E472
D
L
L
W
N
E
I
E
T
T
N
T
S
K
I
Zebra Danio
Brachydanio rerio
XP_698412
751
83510
T482
R
L
D
D
V
G
G
T
S
A
V
I
D
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193303
888
97429
Q592
A
P
G
K
P
V
L
Q
P
K
S
S
N
R
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.1
99.7
92.8
N.A.
97.8
25.6
N.A.
41.6
29.4
43.2
57.7
N.A.
N.A.
N.A.
N.A.
23.3
Protein Similarity:
100
84.4
99.7
93.1
N.A.
98.9
42
N.A.
59.9
41.8
62.1
72.9
N.A.
N.A.
N.A.
N.A.
39.3
P-Site Identity:
100
13.3
100
100
N.A.
100
0
N.A.
6.6
20
0
40
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
26.6
100
100
N.A.
100
0
N.A.
33.3
46.6
6.6
73.3
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
0
10
10
10
0
46
0
0
0
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
10
0
19
10
0
0
0
10
10
0
0
0
10
10
0
% D
% Glu:
0
10
37
46
0
10
0
10
10
10
0
0
37
0
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
10
10
0
0
10
46
0
0
0
10
0
0
10
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
10
0
0
0
0
0
10
0
0
0
0
19
0
0
19
% I
% Lys:
0
0
0
10
0
0
0
10
10
19
0
0
0
19
0
% K
% Leu:
0
19
10
0
10
0
10
0
0
0
46
37
0
0
19
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
10
0
19
37
0
% N
% Pro:
0
19
0
0
10
0
0
0
10
0
0
0
0
0
37
% P
% Gln:
19
0
0
0
0
10
0
10
0
10
0
0
0
0
0
% Q
% Arg:
46
37
0
0
0
37
0
0
0
0
0
0
0
19
0
% R
% Ser:
0
0
0
10
0
0
19
0
55
10
10
19
19
0
10
% S
% Thr:
0
10
0
0
0
10
0
55
10
10
0
10
0
0
10
% T
% Val:
0
0
10
0
64
10
0
0
0
0
19
10
10
10
0
% V
% Trp:
0
0
0
10
10
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _