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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTC21B All Species: 24.55
Human Site: S35 Identified Species: 45
UniProt: Q7Z4L5 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z4L5 NP_079029.3 1316 150939 S35 E G I K R Y G S D P V F R F Y
Chimpanzee Pan troglodytes XP_516376 1320 150978 N37 V G L E K F S N D P V L K F F
Rhesus Macaque Macaca mulatta XP_001096248 1505 171528 S224 E G I K R Y G S D P V F R F Y
Dog Lupus familis XP_850862 1358 155071 N77 E G V K R Y A N D P V F R F Y
Cat Felis silvestris
Mouse Mus musculus Q0HA38 1315 150776 S35 E G M K K Y S S D P V F R F Y
Rat Rattus norvegicus XP_229983 1315 150789 S35 E G M K K Y S S D P V F R F Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513615 1329 151533 S35 E G L K R H G S D P I F M F Y
Chicken Gallus gallus XP_422022 1352 153873 S71 E A L G R L G S D P V F Q F Y
Frog Xenopus laevis Q6INC1 1312 148653 N37 E G L K K Y S N D P V L Q F F
Zebra Danio Brachydanio rerio NP_001121730 1321 150895 P40 E A Q R K F S P D P I F T F L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396105 1491 170258 E38 S I A Y M K N E N V E K T T I
Nematode Worm Caenorhab. elegans Q20255 1332 152170 D57 G R L A T I K D P A L A I L K
Sea Urchin Strong. purpuratus XP_793431 1316 149470 S37 E A I K K Y G S D P V L M F F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 51.4 85.8 87.1 N.A. 85.8 86 N.A. 73.3 74.1 54.7 68.1 N.A. N.A. 34 30.2 57.6
Protein Similarity: 100 71.6 86.9 93 N.A. 93.4 93.3 N.A. 85.5 85.9 73.8 83.9 N.A. N.A. 53 51.7 76.8
P-Site Identity: 100 33.3 100 80 N.A. 80 80 N.A. 73.3 66.6 53.3 33.3 N.A. N.A. 0 0 66.6
P-Site Similarity: 100 80 100 93.3 N.A. 93.3 93.3 N.A. 93.3 80 86.6 60 N.A. N.A. 6.6 13.3 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 24 8 8 0 0 8 0 0 8 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 8 85 0 0 0 0 0 0 % D
% Glu: 77 0 0 8 0 0 0 8 0 0 8 0 0 0 0 % E
% Phe: 0 0 0 0 0 16 0 0 0 0 0 62 0 85 24 % F
% Gly: 8 62 0 8 0 0 39 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 24 0 0 8 0 0 0 0 16 0 8 0 8 % I
% Lys: 0 0 0 62 47 8 8 0 0 0 0 8 8 0 8 % K
% Leu: 0 0 39 0 0 8 0 0 0 0 8 24 0 8 8 % L
% Met: 0 0 16 0 8 0 0 0 0 0 0 0 16 0 0 % M
% Asn: 0 0 0 0 0 0 8 24 8 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 8 8 85 0 0 0 0 0 % P
% Gln: 0 0 8 0 0 0 0 0 0 0 0 0 16 0 0 % Q
% Arg: 0 8 0 8 39 0 0 0 0 0 0 0 39 0 0 % R
% Ser: 8 0 0 0 0 0 39 54 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 8 0 0 0 0 0 0 0 16 8 0 % T
% Val: 8 0 8 0 0 0 0 0 0 8 70 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 54 0 0 0 0 0 0 0 0 54 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _