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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTC21B
All Species:
17.27
Human Site:
S604
Identified Species:
31.67
UniProt:
Q7Z4L5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z4L5
NP_079029.3
1316
150939
S604
R
I
G
A
S
T
K
S
K
D
R
K
T
E
V
Chimpanzee
Pan troglodytes
XP_516376
1320
150978
L613
K
E
E
G
R
K
F
L
R
P
S
V
Q
P
S
Rhesus Macaque
Macaca mulatta
XP_001096248
1505
171528
S793
R
I
G
A
S
T
K
S
K
D
R
K
T
E
V
Dog
Lupus familis
XP_850862
1358
155071
S646
R
I
G
S
S
S
K
S
K
Y
R
K
T
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q0HA38
1315
150776
S604
R
S
R
A
S
S
K
S
K
H
R
T
E
V
D
Rat
Rattus norvegicus
XP_229983
1315
150789
S604
R
S
R
A
S
S
K
S
K
H
R
S
E
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513615
1329
151533
S604
R
I
A
M
S
S
K
S
K
Y
R
S
P
E
I
Chicken
Gallus gallus
XP_422022
1352
153873
M640
K
H
T
A
S
S
K
M
K
G
K
R
I
E
I
Frog
Xenopus laevis
Q6INC1
1312
148653
T605
R
G
A
L
K
K
S
T
W
G
S
L
N
S
S
Zebra Danio
Brachydanio rerio
NP_001121730
1321
150895
R609
R
T
G
S
S
A
K
R
Q
S
K
R
V
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396105
1491
170258
K561
I
V
I
I
Q
D
A
K
V
N
L
G
N
T
S
Nematode Worm
Caenorhab. elegans
Q20255
1332
152170
P623
P
S
K
N
L
F
Q
P
K
E
S
A
D
T
H
Sea Urchin
Strong. purpuratus
XP_793431
1316
149470
R605
K
R
A
V
S
A
S
R
R
V
K
G
G
P
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.4
85.8
87.1
N.A.
85.8
86
N.A.
73.3
74.1
54.7
68.1
N.A.
N.A.
34
30.2
57.6
Protein Similarity:
100
71.6
86.9
93
N.A.
93.4
93.3
N.A.
85.5
85.9
73.8
83.9
N.A.
N.A.
53
51.7
76.8
P-Site Identity:
100
0
100
80
N.A.
46.6
46.6
N.A.
53.3
33.3
6.6
33.3
N.A.
N.A.
0
6.6
6.6
P-Site Similarity:
100
13.3
100
93.3
N.A.
53.3
53.3
N.A.
66.6
66.6
13.3
66.6
N.A.
N.A.
13.3
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
24
39
0
16
8
0
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
16
0
0
8
0
16
% D
% Glu:
0
8
8
0
0
0
0
0
0
8
0
0
16
47
0
% E
% Phe:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
31
8
0
0
0
0
0
16
0
16
8
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
16
0
0
0
0
8
% H
% Ile:
8
31
8
8
0
0
0
0
0
0
0
0
8
0
24
% I
% Lys:
24
0
8
0
8
16
62
8
62
0
24
24
0
0
0
% K
% Leu:
0
0
0
8
8
0
0
8
0
0
8
8
0
0
8
% L
% Met:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
8
0
0
16
0
0
% N
% Pro:
8
0
0
0
0
0
0
8
0
8
0
0
8
16
0
% P
% Gln:
0
0
0
0
8
0
8
0
8
0
0
0
8
0
0
% Q
% Arg:
62
8
16
0
8
0
0
16
16
0
47
16
0
0
0
% R
% Ser:
0
24
0
16
70
39
16
47
0
8
24
16
0
8
24
% S
% Thr:
0
8
8
0
0
16
0
8
0
0
0
8
24
16
0
% T
% Val:
0
8
0
8
0
0
0
0
8
8
0
8
8
16
24
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
16
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _