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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTC21B
All Species:
12.12
Human Site:
S614
Identified Species:
22.22
UniProt:
Q7Z4L5
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z4L5
NP_079029.3
1316
150939
S614
R
K
T
E
V
D
T
S
H
R
L
S
I
F
L
Chimpanzee
Pan troglodytes
XP_516376
1320
150978
A623
S
V
Q
P
S
Q
R
A
S
I
L
L
E
L
V
Rhesus Macaque
Macaca mulatta
XP_001096248
1505
171528
S803
R
K
T
E
V
D
T
S
H
R
L
S
I
F
L
Dog
Lupus familis
XP_850862
1358
155071
N656
R
K
T
E
V
D
A
N
H
R
L
S
I
F
L
Cat
Felis silvestris
Mouse
Mus musculus
Q0HA38
1315
150776
H614
R
T
E
V
D
A
S
H
R
L
S
I
F
L
E
Rat
Rattus norvegicus
XP_229983
1315
150789
H614
R
S
E
V
D
G
S
H
R
L
S
I
F
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513615
1329
151533
N614
R
S
P
E
I
D
A
N
S
R
L
S
I
F
L
Chicken
Gallus gallus
XP_422022
1352
153873
S650
K
R
I
E
I
D
A
S
D
R
V
A
V
F
L
Frog
Xenopus laevis
Q6INC1
1312
148653
V615
S
L
N
S
S
D
K
V
S
I
Y
L
E
L
A
Zebra Danio
Brachydanio rerio
NP_001121730
1321
150895
A619
K
R
V
E
L
S
S
A
D
C
V
S
V
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396105
1491
170258
G571
L
G
N
T
S
E
E
G
K
I
L
I
G
N
A
Nematode Worm
Caenorhab. elegans
Q20255
1332
152170
S633
S
A
D
T
H
K
I
S
V
Q
L
E
L
I
D
Sea Urchin
Strong. purpuratus
XP_793431
1316
149470
T615
K
G
G
P
I
S
M
T
D
R
V
S
V
F
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.4
85.8
87.1
N.A.
85.8
86
N.A.
73.3
74.1
54.7
68.1
N.A.
N.A.
34
30.2
57.6
Protein Similarity:
100
71.6
86.9
93
N.A.
93.4
93.3
N.A.
85.5
85.9
73.8
83.9
N.A.
N.A.
53
51.7
76.8
P-Site Identity:
100
6.6
100
86.6
N.A.
6.6
6.6
N.A.
60
40
6.6
26.6
N.A.
N.A.
6.6
13.3
26.6
P-Site Similarity:
100
20
100
93.3
N.A.
13.3
13.3
N.A.
73.3
80
6.6
73.3
N.A.
N.A.
13.3
26.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
8
24
16
0
0
0
8
0
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
8
0
16
47
0
0
24
0
0
0
0
0
8
% D
% Glu:
0
0
16
47
0
8
8
0
0
0
0
8
16
0
16
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
16
54
0
% F
% Gly:
0
16
8
0
0
8
0
8
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
8
0
0
16
24
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
24
0
8
0
0
24
0
24
31
8
0
% I
% Lys:
24
24
0
0
0
8
8
0
8
0
0
0
0
0
0
% K
% Leu:
8
8
0
0
8
0
0
0
0
16
54
16
8
31
54
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
16
0
0
0
0
16
0
0
0
0
0
8
0
% N
% Pro:
0
0
8
16
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
8
0
0
0
8
0
0
0
0
0
% Q
% Arg:
47
16
0
0
0
0
8
0
16
47
0
0
0
0
0
% R
% Ser:
24
16
0
8
24
16
24
31
24
0
16
47
0
0
0
% S
% Thr:
0
8
24
16
0
0
16
8
0
0
0
0
0
0
0
% T
% Val:
0
8
8
16
24
0
0
8
8
0
24
0
24
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _