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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTC21B
All Species:
4.55
Human Site:
T178
Identified Species:
8.33
UniProt:
Q7Z4L5
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z4L5
NP_079029.3
1316
150939
T178
G
L
Q
D
G
N
D
T
F
A
L
L
G
K
A
Chimpanzee
Pan troglodytes
XP_516376
1320
150978
V180
G
I
Q
D
T
K
D
V
L
G
L
M
G
K
A
Rhesus Macaque
Macaca mulatta
XP_001096248
1505
171528
T367
G
L
Q
D
G
N
D
T
F
A
L
L
G
K
A
Dog
Lupus familis
XP_850862
1358
155071
I220
E
L
Q
D
G
N
D
I
F
A
L
L
G
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q0HA38
1315
150776
I178
G
L
Q
D
G
N
D
I
F
A
L
L
G
K
V
Rat
Rattus norvegicus
XP_229983
1315
150789
I178
G
L
Q
D
G
N
D
I
F
A
L
L
G
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513615
1329
151533
I178
G
M
Q
D
L
S
D
I
F
A
Q
L
G
K
A
Chicken
Gallus gallus
XP_422022
1352
153873
V214
A
L
Q
E
G
N
D
V
F
A
L
L
G
K
A
Frog
Xenopus laevis
Q6INC1
1312
148653
I180
G
I
Q
D
N
K
D
I
F
A
L
I
G
K
A
Zebra Danio
Brachydanio rerio
NP_001121730
1321
150895
I183
A
L
K
E
K
S
D
I
F
A
L
M
G
K
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396105
1491
170258
Q175
L
V
E
K
L
Y
N
Q
L
G
M
K
D
W
D
Nematode Worm
Caenorhab. elegans
Q20255
1332
152170
E197
F
E
K
A
G
G
Q
E
Y
P
D
G
N
I
G
Sea Urchin
Strong. purpuratus
XP_793431
1316
149470
D180
E
V
L
R
C
A
I
D
A
L
I
G
K
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.4
85.8
87.1
N.A.
85.8
86
N.A.
73.3
74.1
54.7
68.1
N.A.
N.A.
34
30.2
57.6
Protein Similarity:
100
71.6
86.9
93
N.A.
93.4
93.3
N.A.
85.5
85.9
73.8
83.9
N.A.
N.A.
53
51.7
76.8
P-Site Identity:
100
53.3
100
86.6
N.A.
86.6
86.6
N.A.
66.6
80
66.6
46.6
N.A.
N.A.
0
6.6
0
P-Site Similarity:
100
66.6
100
86.6
N.A.
86.6
86.6
N.A.
80
86.6
80
73.3
N.A.
N.A.
26.6
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
8
0
8
0
0
8
70
0
0
0
0
54
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
62
0
0
77
8
0
0
8
0
8
0
8
% D
% Glu:
16
8
8
16
0
0
0
8
0
0
0
0
0
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
70
0
0
0
0
0
0
% F
% Gly:
54
0
0
0
54
8
0
0
0
16
0
16
77
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
16
0
0
0
0
8
47
0
0
8
8
0
8
0
% I
% Lys:
0
0
16
8
8
16
0
0
0
0
0
8
8
77
0
% K
% Leu:
8
54
8
0
16
0
0
0
16
8
70
54
0
0
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
8
16
0
0
0
% M
% Asn:
0
0
0
0
8
47
8
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
0
0
70
0
0
0
8
8
0
0
8
0
0
0
0
% Q
% Arg:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
0
0
0
0
0
16
0
0
0
0
0
0
0
8
0
% S
% Thr:
0
0
0
0
8
0
0
16
0
0
0
0
0
0
0
% T
% Val:
0
16
0
0
0
0
0
16
0
0
0
0
0
0
24
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _