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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTC21B
All Species:
33.94
Human Site:
T349
Identified Species:
62.22
UniProt:
Q7Z4L5
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z4L5
NP_079029.3
1316
150939
T349
E
A
L
K
W
Y
K
T
A
M
T
L
D
E
T
Chimpanzee
Pan troglodytes
XP_516376
1320
150978
E359
E
A
L
L
W
Y
S
E
A
M
K
L
D
K
D
Rhesus Macaque
Macaca mulatta
XP_001096248
1505
171528
T538
E
A
L
K
W
Y
K
T
A
M
T
L
D
E
T
Dog
Lupus familis
XP_850862
1358
155071
T391
E
A
L
K
W
Y
K
T
A
L
T
L
D
E
T
Cat
Felis silvestris
Mouse
Mus musculus
Q0HA38
1315
150776
T349
E
A
W
K
W
Y
R
T
A
M
T
L
N
E
S
Rat
Rattus norvegicus
XP_229983
1315
150789
T349
E
A
W
K
W
Y
R
T
A
M
T
L
N
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513615
1329
151533
T349
E
A
L
K
W
Y
E
T
A
M
T
L
D
E
T
Chicken
Gallus gallus
XP_422022
1352
153873
T385
E
A
L
K
W
Y
Q
T
A
M
T
L
D
E
T
Frog
Xenopus laevis
Q6INC1
1312
148653
T350
E
A
A
G
W
Y
A
T
A
M
K
L
D
G
N
Zebra Danio
Brachydanio rerio
NP_001121730
1321
150895
T354
E
A
M
K
W
Y
K
T
A
M
T
L
D
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396105
1491
170258
Q336
A
S
D
L
A
Q
Q
Q
I
D
F
L
M
E
I
Nematode Worm
Caenorhab. elegans
Q20255
1332
152170
L370
V
S
T
L
S
Q
E
L
V
A
L
D
C
E
D
Sea Urchin
Strong. purpuratus
XP_793431
1316
149470
M350
D
A
V
K
A
Y
R
M
A
M
K
L
D
E
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.4
85.8
87.1
N.A.
85.8
86
N.A.
73.3
74.1
54.7
68.1
N.A.
N.A.
34
30.2
57.6
Protein Similarity:
100
71.6
86.9
93
N.A.
93.4
93.3
N.A.
85.5
85.9
73.8
83.9
N.A.
N.A.
53
51.7
76.8
P-Site Identity:
100
60
100
93.3
N.A.
73.3
73.3
N.A.
93.3
93.3
60
86.6
N.A.
N.A.
13.3
6.6
60
P-Site Similarity:
100
66.6
100
100
N.A.
93.3
93.3
N.A.
100
100
60
100
N.A.
N.A.
26.6
20
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
85
8
0
16
0
8
0
85
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
8
0
8
0
0
0
0
0
0
8
0
8
70
0
16
% D
% Glu:
77
0
0
0
0
0
16
8
0
0
0
0
0
85
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% I
% Lys:
0
0
0
70
0
0
31
0
0
0
24
0
0
8
0
% K
% Leu:
0
0
47
24
0
0
0
8
0
8
8
93
0
0
0
% L
% Met:
0
0
8
0
0
0
0
8
0
77
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
16
16
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
24
0
0
0
0
0
0
0
0
% R
% Ser:
0
16
0
0
8
0
8
0
0
0
0
0
0
0
24
% S
% Thr:
0
0
8
0
0
0
0
70
0
0
62
0
0
0
47
% T
% Val:
8
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
16
0
77
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
85
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _