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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTC21B All Species: 29.09
Human Site: Y1282 Identified Species: 53.33
UniProt: Q7Z4L5 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z4L5 NP_079029.3 1316 150939 Y1282 N Y L K A K R Y V D S I D I C
Chimpanzee Pan troglodytes XP_516376 1320 150978 F1286 N Y L K D K K F V E A I E I C
Rhesus Macaque Macaca mulatta XP_001096248 1505 171528 Y1471 N Y L K A K R Y V D S I D I C
Dog Lupus familis XP_850862 1358 155071 Y1324 N Y L K A K R Y V D A I D I C
Cat Felis silvestris
Mouse Mus musculus Q0HA38 1315 150776 Y1281 N Y L K A K R Y V D A I D V C
Rat Rattus norvegicus XP_229983 1315 150789 Y1281 N Y L K A K R Y V D A I D V C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513615 1329 151533 D1288 S A T R F A N D F R E H V P Q
Chicken Gallus gallus XP_422022 1352 153873 Y1318 N Y L K G K R Y V D A I A I C
Frog Xenopus laevis Q6INC1 1312 148653 Y1278 N Y L K D K K Y V D A I D I C
Zebra Danio Brachydanio rerio NP_001121730 1321 150895 H1287 N Y L K A K R H V D A I D V C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396105 1491 170258 Y1197 C S M K A K A Y A D G I E A C
Nematode Worm Caenorhab. elegans Q20255 1332 152170 L1298 T Y L K A K R L F A C I E T C
Sea Urchin Strong. purpuratus XP_793431 1316 149470 F1282 N Y M K A K R F V D A I D I C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 51.4 85.8 87.1 N.A. 85.8 86 N.A. 73.3 74.1 54.7 68.1 N.A. N.A. 34 30.2 57.6
Protein Similarity: 100 71.6 86.9 93 N.A. 93.4 93.3 N.A. 85.5 85.9 73.8 83.9 N.A. N.A. 53 51.7 76.8
P-Site Identity: 100 60 100 93.3 N.A. 86.6 86.6 N.A. 0 80 80 80 N.A. N.A. 46.6 53.3 80
P-Site Similarity: 100 93.3 100 100 N.A. 100 100 N.A. 13.3 86.6 93.3 100 N.A. N.A. 60 60 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 70 8 8 0 8 8 62 0 8 8 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 8 0 0 0 93 % C
% Asp: 0 0 0 0 16 0 0 8 0 77 0 0 62 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 8 8 0 24 0 0 % E
% Phe: 0 0 0 0 8 0 0 16 16 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 8 0 0 0 0 0 8 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 8 0 0 0 8 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 93 0 54 0 % I
% Lys: 0 0 0 93 0 93 16 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 77 0 0 0 0 8 0 0 0 0 0 0 0 % L
% Met: 0 0 16 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 77 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % Q
% Arg: 0 0 0 8 0 0 70 0 0 8 0 0 0 0 0 % R
% Ser: 8 8 0 0 0 0 0 0 0 0 16 0 0 0 0 % S
% Thr: 8 0 8 0 0 0 0 0 0 0 0 0 0 8 0 % T
% Val: 0 0 0 0 0 0 0 0 77 0 0 0 8 24 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 85 0 0 0 0 0 62 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _