KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTC21B
All Species:
17.27
Human Site:
Y255
Identified Species:
31.67
UniProt:
Q7Z4L5
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z4L5
NP_079029.3
1316
150939
Y255
A
L
R
M
Q
A
L
Y
Y
V
C
R
E
G
D
Chimpanzee
Pan troglodytes
XP_516376
1320
150978
H257
A
C
Q
I
L
T
V
H
E
L
A
R
E
G
N
Rhesus Macaque
Macaca mulatta
XP_001096248
1505
171528
Y444
A
L
R
M
Q
A
L
Y
Y
V
C
R
E
G
D
Dog
Lupus familis
XP_850862
1358
155071
Y297
A
L
R
I
L
A
L
Y
Y
L
C
R
E
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q0HA38
1315
150776
Y255
A
L
R
M
L
A
L
Y
Y
L
C
R
E
G
D
Rat
Rattus norvegicus
XP_229983
1315
150789
Y255
A
L
R
M
L
A
L
Y
Y
L
C
R
E
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513615
1329
151533
H255
A
L
R
M
L
A
L
H
H
L
C
R
E
G
N
Chicken
Gallus gallus
XP_422022
1352
153873
H291
A
T
R
M
E
A
L
H
F
L
C
R
E
G
K
Frog
Xenopus laevis
Q6INC1
1312
148653
H257
A
F
Q
I
L
T
I
H
S
V
T
R
E
G
S
Zebra Danio
Brachydanio rerio
NP_001121730
1321
150895
H260
A
L
R
M
Q
A
L
H
A
L
C
R
D
G
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396105
1491
170258
L247
I
L
V
N
N
I
Q
L
F
S
R
I
A
C
K
Nematode Worm
Caenorhab. elegans
Q20255
1332
152170
H276
I
E
V
L
R
T
V
H
G
I
C
Y
A
G
E
Sea Urchin
Strong. purpuratus
XP_793431
1316
149470
Q256
A
L
R
L
I
I
L
Q
I
L
C
R
E
G
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.4
85.8
87.1
N.A.
85.8
86
N.A.
73.3
74.1
54.7
68.1
N.A.
N.A.
34
30.2
57.6
Protein Similarity:
100
71.6
86.9
93
N.A.
93.4
93.3
N.A.
85.5
85.9
73.8
83.9
N.A.
N.A.
53
51.7
76.8
P-Site Identity:
100
26.6
100
80
N.A.
86.6
86.6
N.A.
66.6
60
33.3
73.3
N.A.
N.A.
6.6
13.3
53.3
P-Site Similarity:
100
66.6
100
93.3
N.A.
93.3
93.3
N.A.
93.3
86.6
60
93.3
N.A.
N.A.
13.3
53.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
85
0
0
0
0
62
0
0
8
0
8
0
16
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
77
0
0
8
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
47
% D
% Glu:
0
8
0
0
8
0
0
0
8
0
0
0
77
0
8
% E
% Phe:
0
8
0
0
0
0
0
0
16
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
0
0
0
0
93
0
% G
% His:
0
0
0
0
0
0
0
47
8
0
0
0
0
0
0
% H
% Ile:
16
0
0
24
8
16
8
0
8
8
0
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% K
% Leu:
0
70
0
16
47
0
70
8
0
62
0
0
0
0
0
% L
% Met:
0
0
0
54
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
24
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
16
0
24
0
8
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
70
0
8
0
0
0
0
0
8
85
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
8
% S
% Thr:
0
8
0
0
0
24
0
0
0
0
8
0
0
0
0
% T
% Val:
0
0
16
0
0
0
16
0
0
24
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
39
39
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _