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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LRRC67 All Species: 13.03
Human Site: Y280 Identified Species: 26.06
UniProt: Q7Z4L9 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z4L9 NP_001013648.1 355 40902 Y280 M H H I V P V Y Y P Q V G K P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001098132 357 41194 Y280 M H H I V P V Y Y P Q V G K P
Dog Lupus familis XP_535092 274 31609 L216 K P K Y R D R L I L V S K S L
Cat Felis silvestris
Mouse Mus musculus Q8R1Z4 357 41133 Y280 V H H I V P V Y Y P Q V G K P
Rat Rattus norvegicus Q6AYH9 633 69937 L497 L E L E E L P L S V F E G T P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511564 352 40695 Y280 D N H L V P V Y Y D S P Q G G
Chicken Gallus gallus XP_418281 319 36494 M256 R K K S K G R M T N E H A D Y
Frog Xenopus laevis Q5PPX0 372 42680 N279 R S L L P V Y N Q N F R H Q L
Zebra Danio Brachydanio rerio Q6GQN5 329 37454 A264 K D N K L Q V A N Q L S T S A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P45969 326 37341 N260 V E R L E S L N D F W A N D N
Sea Urchin Strong. purpuratus XP_786243 353 39917 P281 R E L P P V L P P N G S R W N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36047 338 38869 T272 L N H L S N L T D I W A S F N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 97.1 69.8 N.A. 82.9 20.2 N.A. 69.8 54.9 50.8 47.6 N.A. N.A. N.A. 20.8 43.3
Protein Similarity: 100 N.A. 98 73.8 N.A. 91.3 34.4 N.A. 80.2 69.8 69 65.9 N.A. N.A. N.A. 39.4 64.7
P-Site Identity: 100 N.A. 100 0 N.A. 93.3 13.3 N.A. 40 0 0 6.6 N.A. N.A. N.A. 0 0
P-Site Similarity: 100 N.A. 100 0 N.A. 100 20 N.A. 53.3 6.6 13.3 20 N.A. N.A. N.A. 20 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 41.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 9 0 0 0 17 9 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 9 0 0 0 9 0 0 17 9 0 0 0 17 0 % D
% Glu: 0 25 0 9 17 0 0 0 0 0 9 9 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 9 17 0 0 9 0 % F
% Gly: 0 0 0 0 0 9 0 0 0 0 9 0 34 9 9 % G
% His: 0 25 42 0 0 0 0 0 0 0 0 9 9 0 0 % H
% Ile: 0 0 0 25 0 0 0 0 9 9 0 0 0 0 0 % I
% Lys: 17 9 17 9 9 0 0 0 0 0 0 0 9 25 0 % K
% Leu: 17 0 25 34 9 9 25 17 0 9 9 0 0 0 17 % L
% Met: 17 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % M
% Asn: 0 17 9 0 0 9 0 17 9 25 0 0 9 0 25 % N
% Pro: 0 9 0 9 17 34 9 9 9 25 0 9 0 0 34 % P
% Gln: 0 0 0 0 0 9 0 0 9 9 25 0 9 9 0 % Q
% Arg: 25 0 9 0 9 0 17 0 0 0 0 9 9 0 0 % R
% Ser: 0 9 0 9 9 9 0 0 9 0 9 25 9 17 0 % S
% Thr: 0 0 0 0 0 0 0 9 9 0 0 0 9 9 0 % T
% Val: 17 0 0 0 34 17 42 0 0 9 9 25 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 17 0 0 9 0 % W
% Tyr: 0 0 0 9 0 0 9 34 34 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _