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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRRC67
All Species:
12.73
Human Site:
Y281
Identified Species:
25.45
UniProt:
Q7Z4L9
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z4L9
NP_001013648.1
355
40902
Y281
H
H
I
V
P
V
Y
Y
P
Q
V
G
K
P
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001098132
357
41194
Y281
H
H
I
V
P
V
Y
Y
P
Q
V
G
K
P
K
Dog
Lupus familis
XP_535092
274
31609
I217
P
K
Y
R
D
R
L
I
L
V
S
K
S
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8R1Z4
357
41133
Y281
H
H
I
V
P
V
Y
Y
P
Q
V
G
K
P
K
Rat
Rattus norvegicus
Q6AYH9
633
69937
S498
E
L
E
E
L
P
L
S
V
F
E
G
T
P
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511564
352
40695
Y281
N
H
L
V
P
V
Y
Y
D
S
P
Q
G
G
K
Chicken
Gallus gallus
XP_418281
319
36494
T257
K
K
S
K
G
R
M
T
N
E
H
A
D
Y
L
Frog
Xenopus laevis
Q5PPX0
372
42680
Q280
S
L
L
P
V
Y
N
Q
N
F
R
H
Q
L
L
Zebra Danio
Brachydanio rerio
Q6GQN5
329
37454
N265
D
N
K
L
Q
V
A
N
Q
L
S
T
S
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P45969
326
37341
D261
E
R
L
E
S
L
N
D
F
W
A
N
D
N
K
Sea Urchin
Strong. purpuratus
XP_786243
353
39917
P282
E
L
P
P
V
L
P
P
N
G
S
R
W
N
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P36047
338
38869
D273
N
H
L
S
N
L
T
D
I
W
A
S
F
N
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.1
69.8
N.A.
82.9
20.2
N.A.
69.8
54.9
50.8
47.6
N.A.
N.A.
N.A.
20.8
43.3
Protein Similarity:
100
N.A.
98
73.8
N.A.
91.3
34.4
N.A.
80.2
69.8
69
65.9
N.A.
N.A.
N.A.
39.4
64.7
P-Site Identity:
100
N.A.
100
0
N.A.
100
13.3
N.A.
46.6
0
0
6.6
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
100
N.A.
100
6.6
N.A.
100
13.3
N.A.
60
6.6
13.3
20
N.A.
N.A.
N.A.
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
0
0
0
17
9
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
9
0
0
17
9
0
0
0
17
0
9
% D
% Glu:
25
0
9
17
0
0
0
0
0
9
9
0
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
9
17
0
0
9
0
0
% F
% Gly:
0
0
0
0
9
0
0
0
0
9
0
34
9
9
0
% G
% His:
25
42
0
0
0
0
0
0
0
0
9
9
0
0
0
% H
% Ile:
0
0
25
0
0
0
0
9
9
0
0
0
0
0
9
% I
% Lys:
9
17
9
9
0
0
0
0
0
0
0
9
25
0
50
% K
% Leu:
0
25
34
9
9
25
17
0
9
9
0
0
0
17
17
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
17
9
0
0
9
0
17
9
25
0
0
9
0
25
0
% N
% Pro:
9
0
9
17
34
9
9
9
25
0
9
0
0
34
0
% P
% Gln:
0
0
0
0
9
0
0
9
9
25
0
9
9
0
0
% Q
% Arg:
0
9
0
9
0
17
0
0
0
0
9
9
0
0
9
% R
% Ser:
9
0
9
9
9
0
0
9
0
9
25
9
17
0
0
% S
% Thr:
0
0
0
0
0
0
9
9
0
0
0
9
9
0
0
% T
% Val:
0
0
0
34
17
42
0
0
9
9
25
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
17
0
0
9
0
0
% W
% Tyr:
0
0
9
0
0
9
34
34
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _