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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRPM1
All Species:
31.21
Human Site:
S290
Identified Species:
76.3
UniProt:
Q7Z4N2
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z4N2
NP_002411.3
1603
182178
S290
G
R
A
S
D
I
L
S
F
A
H
K
Y
C
E
Chimpanzee
Pan troglodytes
XP_510268
1745
197782
S432
G
R
A
S
D
I
L
S
F
A
H
K
Y
C
E
Rhesus Macaque
Macaca mulatta
XP_001116180
1648
187321
S335
G
R
A
S
D
I
L
S
F
A
H
K
Y
C
E
Dog
Lupus familis
XP_545816
1774
201215
S453
G
R
A
S
D
I
L
S
F
A
H
K
Y
C
E
Cat
Felis silvestris
Mouse
Mus musculus
Q2TV84
1622
183508
S336
G
R
A
S
D
I
L
S
F
A
H
K
Y
C
D
Rat
Rattus norvegicus
Q2WEA5
1628
184300
S336
G
R
A
S
D
I
L
S
F
A
H
K
Y
C
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509922
1690
191857
S365
G
R
A
S
D
I
L
S
F
A
H
K
Y
S
E
Chicken
Gallus gallus
XP_425066
1665
188778
S344
G
R
A
S
D
I
L
S
F
A
H
K
Y
S
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A8DYE2
2023
225520
A412
G
R
A
A
D
L
L
A
F
V
H
K
Y
A
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q93971
2032
229044
A611
G
R
A
A
D
L
L
A
F
A
H
Q
N
V
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.4
95.6
82
N.A.
85.6
85.6
N.A.
78.4
78.1
N.A.
N.A.
N.A.
36.1
N.A.
26.8
N.A.
Protein Similarity:
100
91.6
96.2
85.9
N.A.
90.8
90.5
N.A.
86.1
85.5
N.A.
N.A.
N.A.
52.2
N.A.
44.3
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
60
N.A.
53.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
N.A.
N.A.
80
N.A.
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
100
20
0
0
0
20
0
90
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
60
0
% C
% Asp:
0
0
0
0
100
0
0
0
0
0
0
0
0
0
20
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
60
% E
% Phe:
0
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% F
% Gly:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% H
% Ile:
0
0
0
0
0
80
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
90
0
0
0
% K
% Leu:
0
0
0
0
0
20
100
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
80
0
0
0
80
0
0
0
0
0
20
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
90
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _