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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GDF7 All Species: 8.48
Human Site: T175 Identified Species: 16.97
UniProt: Q7Z4P5 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z4P5 NP_878248.2 450 46950 T175 E S G P G S W T S P P L L L L
Chimpanzee Pan troglodytes XP_001164592 501 55399 G258 K P A A P G G G R A A Q L K L
Rhesus Macaque Macaca mulatta XP_001096970 447 47002 T172 E P G P G S S T S P P L L L L
Dog Lupus familis XP_542974 499 55131 G256 K P V A P S I G R A A Q L K L
Cat Felis silvestris
Mouse Mus musculus P43029 461 47872 T168 E P D R D S A T L L P R L L L
Rat Rattus norvegicus Q6HA10 452 50994 W178 R Q A P P T P W G P Q T R P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511410 181 19862
Chicken Gallus gallus Q90751 353 40328 H126 E S N S S Y H H R I N I Y E I
Frog Xenopus laevis P25703 398 45557 E164 E Q V Q E P F E S D S S K L H
Zebra Danio Brachydanio rerio P85857 404 46271 N162 P S P S G V Y N L H L L S C R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P07713 588 65849 S207 E Q G P S T Y S K E A L I K D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P48969 461 51863 R216 R Q G R S L Y R I D V L L L R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 31.1 95.1 30.8 N.A. 81.1 45.1 N.A. 29.7 26 28.8 42.4 N.A. 25 N.A. N.A. 20.6
Protein Similarity: 100 43.7 96.2 42.8 N.A. 84.8 55.9 N.A. 34 39.3 42.4 56.6 N.A. 39.1 N.A. N.A. 33.8
P-Site Identity: 100 13.3 86.6 20 N.A. 46.6 20 N.A. 0 13.3 20 20 N.A. 26.6 N.A. N.A. 26.6
P-Site Similarity: 100 20 86.6 26.6 N.A. 46.6 26.6 N.A. 0 26.6 26.6 26.6 N.A. 53.3 N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 17 17 0 0 9 0 0 17 25 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % C
% Asp: 0 0 9 0 9 0 0 0 0 17 0 0 0 0 9 % D
% Glu: 50 0 0 0 9 0 0 9 0 9 0 0 0 9 0 % E
% Phe: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 34 0 25 9 9 17 9 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 9 9 0 9 0 0 0 0 9 % H
% Ile: 0 0 0 0 0 0 9 0 9 9 0 9 9 0 9 % I
% Lys: 17 0 0 0 0 0 0 0 9 0 0 0 9 25 0 % K
% Leu: 0 0 0 0 0 9 0 0 17 9 9 42 50 42 50 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 0 0 0 9 0 0 9 0 0 0 0 % N
% Pro: 9 34 9 34 25 9 9 0 0 25 25 0 0 9 0 % P
% Gln: 0 34 0 9 0 0 0 0 0 0 9 17 0 0 0 % Q
% Arg: 17 0 0 17 0 0 0 9 25 0 0 9 9 0 17 % R
% Ser: 0 25 0 17 25 34 9 9 25 0 9 9 9 0 0 % S
% Thr: 0 0 0 0 0 17 0 25 0 0 0 9 0 0 0 % T
% Val: 0 0 17 0 0 9 0 0 0 0 9 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 9 9 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 25 0 0 0 0 0 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _