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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEATR3
All Species:
19.7
Human Site:
S144
Identified Species:
43.33
UniProt:
Q7Z4Q2
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z4Q2
NP_891552.1
680
74583
S144
G
L
D
S
N
E
M
S
L
Q
E
K
K
D
Q
Chimpanzee
Pan troglodytes
XP_520630
763
83414
S227
G
L
D
S
N
E
M
S
L
Q
E
K
K
D
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535308
680
74553
S144
G
L
D
S
N
E
M
S
P
Q
E
K
K
D
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8BQM4
679
74287
M143
S
G
L
D
S
N
E
M
S
P
Q
E
K
A
D
Rat
Rattus norvegicus
XP_341655
682
74770
S144
G
L
D
S
N
E
M
S
P
Q
E
K
A
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507564
683
74512
S144
G
M
D
S
N
G
V
S
S
R
T
N
K
D
S
Chicken
Gallus gallus
NP_001025740
675
74049
S138
G
L
D
A
N
Q
L
S
P
K
K
R
R
E
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_957183
682
73896
V139
E
C
C
A
G
F
G
V
N
S
P
S
K
K
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649649
625
69159
V113
T
E
V
C
D
F
L
V
E
N
D
I
L
T
A
Honey Bee
Apis mellifera
XP_001120378
587
66891
I75
S
Y
N
S
T
L
A
I
Q
I
T
K
N
G
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796943
514
55629
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.1
N.A.
91.3
N.A.
86.1
86.2
N.A.
79.8
67.9
N.A.
53.8
N.A.
25.4
24.2
N.A.
31.6
Protein Similarity:
100
89.1
N.A.
95.2
N.A.
93
93.2
N.A.
88.4
81.3
N.A.
72.2
N.A.
45.1
46.7
N.A.
46.4
P-Site Identity:
100
100
N.A.
93.3
N.A.
6.6
80
N.A.
46.6
33.3
N.A.
6.6
N.A.
0
13.3
N.A.
0
P-Site Similarity:
100
100
N.A.
93.3
N.A.
26.6
86.6
N.A.
66.6
86.6
N.A.
13.3
N.A.
20
20
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
19
0
0
10
0
0
0
0
0
10
10
10
% A
% Cys:
0
10
10
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
55
10
10
0
0
0
0
0
10
0
0
46
10
% D
% Glu:
10
10
0
0
0
37
10
0
10
0
37
10
0
10
0
% E
% Phe:
0
0
0
0
0
19
0
0
0
0
0
0
0
0
0
% F
% Gly:
55
10
0
0
10
10
10
0
0
0
0
0
0
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
10
0
10
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
10
10
46
55
10
10
% K
% Leu:
0
46
10
0
0
10
19
0
19
0
0
0
10
0
0
% L
% Met:
0
10
0
0
0
0
37
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
55
10
0
0
10
10
0
10
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
28
10
10
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
10
37
10
0
0
0
28
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
0
10
10
0
0
% R
% Ser:
19
0
0
55
10
0
0
55
19
10
0
10
0
0
10
% S
% Thr:
10
0
0
0
10
0
0
0
0
0
19
0
0
10
0
% T
% Val:
0
0
10
0
0
0
10
19
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _