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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEATR3
All Species:
28.48
Human Site:
S650
Identified Species:
62.67
UniProt:
Q7Z4Q2
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z4Q2
NP_891552.1
680
74583
S650
K
E
G
R
G
N
Y
S
T
D
Q
L
C
V
L
Chimpanzee
Pan troglodytes
XP_520630
763
83414
S733
K
E
G
R
G
N
Y
S
T
D
Q
L
C
V
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535308
680
74553
S650
K
E
G
R
G
K
Y
S
P
D
Q
L
C
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BQM4
679
74287
S649
K
E
G
R
G
K
Y
S
P
D
Q
L
C
V
L
Rat
Rattus norvegicus
XP_341655
682
74770
S652
K
E
G
R
A
R
Y
S
P
D
Q
L
C
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507564
683
74512
S653
K
E
G
R
G
K
Y
S
T
D
Q
L
C
V
L
Chicken
Gallus gallus
NP_001025740
675
74049
S646
K
E
G
K
G
Q
Y
S
T
D
Q
L
C
V
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_957183
682
73896
S655
K
E
G
K
G
K
Y
S
P
D
Q
L
C
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649649
625
69159
E600
Q
Q
R
R
E
L
K
E
R
R
A
T
V
Q
T
Honey Bee
Apis mellifera
XP_001120378
587
66891
D561
Q
Q
K
K
T
L
G
D
N
I
A
I
V
S
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796943
514
55629
N489
E
H
L
P
I
I
M
N
A
R
T
N
L
G
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.1
N.A.
91.3
N.A.
86.1
86.2
N.A.
79.8
67.9
N.A.
53.8
N.A.
25.4
24.2
N.A.
31.6
Protein Similarity:
100
89.1
N.A.
95.2
N.A.
93
93.2
N.A.
88.4
81.3
N.A.
72.2
N.A.
45.1
46.7
N.A.
46.4
P-Site Identity:
100
100
N.A.
86.6
N.A.
86.6
80
N.A.
93.3
86.6
N.A.
80
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
100
N.A.
86.6
N.A.
86.6
80
N.A.
93.3
93.3
N.A.
86.6
N.A.
20
26.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
10
0
19
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
73
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
73
0
0
0
0
0
% D
% Glu:
10
73
0
0
10
0
0
10
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
73
0
64
0
10
0
0
0
0
0
0
10
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
10
0
0
0
10
0
10
0
0
0
% I
% Lys:
73
0
10
28
0
37
10
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
10
0
0
19
0
0
0
0
0
73
10
0
73
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
19
0
10
10
0
0
10
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
37
0
0
0
0
0
0
% P
% Gln:
19
19
0
0
0
10
0
0
0
0
73
0
0
10
0
% Q
% Arg:
0
0
10
64
0
10
0
0
10
19
0
0
0
0
10
% R
% Ser:
0
0
0
0
0
0
0
73
0
0
0
0
0
10
0
% S
% Thr:
0
0
0
0
10
0
0
0
37
0
10
10
0
0
19
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
19
73
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
73
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _