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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF21A All Species: 4.55
Human Site: T1157 Identified Species: 9.09
UniProt: Q7Z4S6 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z4S6 NP_060111.2 1674 187179 T1157 K N K A R R R T T T Q M E L L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001099469 1663 184637 S1144 Q Q E N G Y A S T D E E I S E
Dog Lupus familis XP_547366 1470 163982 N972 M Q R M T I V N L E A D M E R
Cat Felis silvestris
Mouse Mus musculus Q9QXL2 1672 186518 A1155 E V K P K N K A R R R T T T Q
Rat Rattus norvegicus Q7M6Z5 1394 158861 K896 Q G E G L H P K A E D T D A F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521746 1544 171654 S1025 Q Q E N G Y A S T D E E I S E
Chicken Gallus gallus Q90640 1225 138905 Q727 L K D A L Q K Q R E A A D K R
Frog Xenopus laevis Q91784 1226 138905 M728 L Q R Q K E A M E K R K D S Q
Zebra Danio Brachydanio rerio Q58G59 1363 154819 T865 Q Q K R R L E T E M Q K G K H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394542 1442 161348 R944 Q L L E H V L R D R D L L S L
Nematode Worm Caenorhab. elegans P46873 699 78760 K201 V G A T L M N K D S S R S H S
Sea Urchin Strong. purpuratus P46871 742 84184 D244 V G K L N L V D L A G S E R Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 56.5 50 N.A. 93.7 24.9 N.A. 55.2 26.8 28.2 23.4 N.A. N.A. 43.9 22.3 22.2
Protein Similarity: 100 N.A. 72.5 64.6 N.A. 96.4 43.9 N.A. 70.8 44.6 43.4 43.1 N.A. N.A. 60.1 30.5 32.5
P-Site Identity: 100 N.A. 6.6 0 N.A. 6.6 0 N.A. 6.6 6.6 0 26.6 N.A. N.A. 6.6 0 13.3
P-Site Similarity: 100 N.A. 33.3 6.6 N.A. 33.3 20 N.A. 33.3 26.6 26.6 33.3 N.A. N.A. 20 6.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 17 0 0 25 9 9 9 17 9 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 0 0 9 17 17 17 9 25 0 0 % D
% Glu: 9 0 25 9 0 9 9 0 17 25 17 17 17 9 17 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % F
% Gly: 0 25 0 9 17 0 0 0 0 0 9 0 9 0 0 % G
% His: 0 0 0 0 9 9 0 0 0 0 0 0 0 9 9 % H
% Ile: 0 0 0 0 0 9 0 0 0 0 0 0 17 0 0 % I
% Lys: 9 9 34 0 17 0 17 17 0 9 0 17 0 17 0 % K
% Leu: 17 9 9 9 25 17 9 0 17 0 0 9 9 9 17 % L
% Met: 9 0 0 9 0 9 0 9 0 9 0 9 9 0 0 % M
% Asn: 0 9 0 17 9 9 9 9 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 9 0 0 9 0 0 0 0 0 0 0 0 % P
% Gln: 42 42 0 9 0 9 0 9 0 0 17 0 0 0 25 % Q
% Arg: 0 0 17 9 17 9 9 9 17 17 17 9 0 9 17 % R
% Ser: 0 0 0 0 0 0 0 17 0 9 9 9 9 34 9 % S
% Thr: 0 0 0 9 9 0 0 17 25 9 0 17 9 9 0 % T
% Val: 17 9 0 0 0 9 17 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 17 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _