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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HDGFRP2
All Species:
11.52
Human Site:
S458
Identified Species:
28.15
UniProt:
Q7Z4V5
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z4V5
NP_001001520.1
671
74317
S458
R
K
R
S
E
G
F
S
M
D
R
K
V
E
K
Chimpanzee
Pan troglodytes
XP_001139142
262
29324
S82
K
F
A
L
K
V
D
S
P
D
V
K
R
C
L
Rhesus Macaque
Macaca mulatta
XP_001082187
397
44271
K217
P
E
E
K
P
Q
A
K
P
V
K
V
E
R
T
Dog
Lupus familis
XP_542154
649
71814
P433
R
K
R
S
E
G
F
P
P
D
R
K
V
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q3UMU9
669
74272
S454
R
K
R
S
E
G
L
S
L
E
R
K
G
E
K
Rat
Rattus norvegicus
Q925G1
669
74000
S454
R
K
R
S
E
G
L
S
L
D
R
K
G
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5XXA9
579
64909
T382
N
K
E
E
G
K
K
T
E
V
K
K
M
E
K
Frog
Xenopus laevis
Q32N87
642
72361
M450
K
E
K
K
K
P
E
M
I
N
S
R
R
V
V
Zebra Danio
Brachydanio rerio
Q5XXA7
662
73469
P465
P
K
R
K
P
V
R
P
P
E
K
K
V
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P52016
466
53547
E286
D
D
R
S
G
R
D
E
R
R
D
D
R
R
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.5
57.3
84
N.A.
82.8
81.2
N.A.
N.A.
33
51.5
50.6
N.A.
N.A.
N.A.
21.9
N.A.
Protein Similarity:
100
38.7
57.9
89.1
N.A.
89.7
88.3
N.A.
N.A.
52.1
64.3
66
N.A.
N.A.
N.A.
35.6
N.A.
P-Site Identity:
100
20
0
86.6
N.A.
73.3
80
N.A.
N.A.
26.6
0
40
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
33.3
13.3
86.6
N.A.
86.6
86.6
N.A.
N.A.
46.6
46.6
53.3
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
10
10
0
0
0
0
20
0
0
40
10
10
0
0
0
% D
% Glu:
0
20
20
10
40
0
10
10
10
20
0
0
10
60
0
% E
% Phe:
0
10
0
0
0
0
20
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
20
40
0
0
0
0
0
0
20
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
20
60
10
30
20
10
10
10
0
0
30
70
0
0
60
% K
% Leu:
0
0
0
10
0
0
20
0
20
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
10
10
0
0
0
10
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
20
0
0
0
20
10
0
20
40
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
40
0
60
0
0
10
10
0
10
10
40
10
30
20
0
% R
% Ser:
0
0
0
50
0
0
0
40
0
0
10
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% T
% Val:
0
0
0
0
0
20
0
0
0
20
10
10
30
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _