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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DCXR All Species: 28.48
Human Site: T67 Identified Species: 52.22
UniProt: Q7Z4W1 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z4W1 NP_057370.1 244 25913 T67 D L G D W E A T E R A L G S V
Chimpanzee Pan troglodytes XP_511756 244 25740 T67 D L G D W E A T E R A L G S V
Rhesus Macaque Macaca mulatta XP_001112983 244 25848 T67 D L G D W E A T E R A L G S V
Dog Lupus familis XP_533135 235 24903 T58 D L G D W E A T E R A L G S V
Cat Felis silvestris
Mouse Mus musculus Q91X52 244 25727 T67 D L A D W E A T E Q A L S N V
Rat Rattus norvegicus Q920P0 244 25701 T67 D L A D W E A T E Q A L S N V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q8JIS3 246 26149 T69 D L A D W D A T E A A V G A A
Frog Xenopus laevis Q6NUE2 236 25189 F66 E N E I Q C T F K E I K N N L
Zebra Danio Brachydanio rerio Q6P0H7 237 24860 V64 D V S K E E E V Q K A F E T I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_397008 244 26471 T67 D L S D W N A T R K A V E S V
Nematode Worm Caenorhab. elegans Q21929 251 27201 L74 V S A N E E V L F K L I V P H
Sea Urchin Strong. purpuratus XP_001198088 228 24155 L56 T N E V L S P L P P F D L L V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ASX2 266 28314 Q83 P E R E K L M Q T V S S M F G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.5 95.4 80.7 N.A. 84.4 84 N.A. N.A. 71.9 29.5 31.1 N.A. N.A. 55.7 48.2 49.1
Protein Similarity: 100 98.3 97.1 87.3 N.A. 91.3 90.5 N.A. N.A. 84.1 46.3 45.9 N.A. N.A. 74.5 67.7 66.3
P-Site Identity: 100 100 100 100 N.A. 73.3 73.3 N.A. N.A. 60 0 20 N.A. N.A. 60 6.6 6.6
P-Site Similarity: 100 100 100 100 N.A. 86.6 86.6 N.A. N.A. 80 26.6 53.3 N.A. N.A. 73.3 26.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. 30.4 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 48.1 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 31 0 0 0 62 0 0 8 70 0 0 8 8 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 70 0 0 62 0 8 0 0 0 0 0 8 0 0 0 % D
% Glu: 8 8 16 8 16 62 8 0 54 8 0 0 16 0 0 % E
% Phe: 0 0 0 0 0 0 0 8 8 0 8 8 0 8 0 % F
% Gly: 0 0 31 0 0 0 0 0 0 0 0 0 39 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 0 0 8 0 0 0 0 0 0 8 8 0 0 8 % I
% Lys: 0 0 0 8 8 0 0 0 8 24 0 8 0 0 0 % K
% Leu: 0 62 0 0 8 8 0 16 0 0 8 47 8 8 8 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 8 0 0 % M
% Asn: 0 16 0 8 0 8 0 0 0 0 0 0 8 24 0 % N
% Pro: 8 0 0 0 0 0 8 0 8 8 0 0 0 8 0 % P
% Gln: 0 0 0 0 8 0 0 8 8 16 0 0 0 0 0 % Q
% Arg: 0 0 8 0 0 0 0 0 8 31 0 0 0 0 0 % R
% Ser: 0 8 16 0 0 8 0 0 0 0 8 8 16 39 0 % S
% Thr: 8 0 0 0 0 0 8 62 8 0 0 0 0 8 0 % T
% Val: 8 8 0 8 0 0 8 8 0 8 0 16 8 0 62 % V
% Trp: 0 0 0 0 62 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _