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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCXR
All Species:
45.15
Human Site:
Y149
Identified Species:
82.78
UniProt:
Q7Z4W1
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z4W1
NP_057370.1
244
25913
Y149
A
V
T
N
H
S
V
Y
C
S
T
K
G
A
L
Chimpanzee
Pan troglodytes
XP_511756
244
25740
Y149
A
V
T
N
H
S
V
Y
C
S
T
K
G
A
L
Rhesus Macaque
Macaca mulatta
XP_001112983
244
25848
Y149
A
V
T
N
H
S
V
Y
C
S
T
K
G
A
L
Dog
Lupus familis
XP_533135
235
24903
Y140
A
I
A
N
H
S
V
Y
C
S
T
K
G
A
M
Cat
Felis silvestris
Mouse
Mus musculus
Q91X52
244
25727
Y149
A
L
T
N
H
T
V
Y
C
S
T
K
G
A
L
Rat
Rattus norvegicus
Q920P0
244
25701
Y149
A
L
T
N
H
T
V
Y
C
S
T
K
G
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q8JIS3
246
26149
Y151
A
L
R
D
H
A
V
Y
C
S
T
K
S
A
L
Frog
Xenopus laevis
Q6NUE2
236
25189
Y147
G
N
I
G
Q
S
I
Y
G
A
S
K
E
G
L
Zebra Danio
Brachydanio rerio
Q6P0H7
237
24860
Y148
G
N
A
G
Q
C
V
Y
S
A
S
K
A
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397008
244
26471
Y149
A
L
K
D
H
V
V
Y
C
A
S
K
G
A
V
Nematode Worm
Caenorhab. elegans
Q21929
251
27201
Y156
P
L
D
N
H
T
V
Y
C
A
S
K
A
A
L
Sea Urchin
Strong. purpuratus
XP_001198088
228
24155
Y131
G
L
T
N
H
A
V
Y
A
S
S
K
G
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ASX2
266
28314
Y164
S
A
S
V
G
S
I
Y
S
A
T
K
G
A
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
95.4
80.7
N.A.
84.4
84
N.A.
N.A.
71.9
29.5
31.1
N.A.
N.A.
55.7
48.2
49.1
Protein Similarity:
100
98.3
97.1
87.3
N.A.
91.3
90.5
N.A.
N.A.
84.1
46.3
45.9
N.A.
N.A.
74.5
67.7
66.3
P-Site Identity:
100
100
100
80
N.A.
86.6
86.6
N.A.
N.A.
66.6
26.6
26.6
N.A.
N.A.
53.3
53.3
66.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
86.6
46.6
40
N.A.
N.A.
86.6
80
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
62
8
16
0
0
16
0
0
8
39
0
0
16
85
0
% A
% Cys:
0
0
0
0
0
8
0
0
70
0
0
0
0
0
0
% C
% Asp:
0
0
8
16
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
24
0
0
16
8
0
0
0
8
0
0
0
70
16
0
% G
% His:
0
0
0
0
77
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
0
0
0
16
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
0
0
0
0
0
0
0
0
100
0
0
0
% K
% Leu:
0
47
0
0
0
0
0
0
0
0
0
0
0
0
85
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
16
0
62
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
8
0
0
47
0
0
16
62
39
0
8
0
0
% S
% Thr:
0
0
47
0
0
24
0
0
0
0
62
0
0
0
0
% T
% Val:
0
24
0
8
0
8
85
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _