KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSD11B1L
All Species:
4.55
Human Site:
T279
Identified Species:
10
UniProt:
Q7Z5J1
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z5J1
NP_940935.1
315
34288
T279
S
S
R
Q
K
S
K
T
E
K
N
D
G
H
L
Chimpanzee
Pan troglodytes
XP_512300
315
34410
T279
S
S
R
Q
K
S
K
T
E
K
N
D
G
H
L
Rhesus Macaque
Macaca mulatta
XP_001110531
292
32393
R273
L
L
M
R
N
P
C
R
K
I
L
E
F
L
Y
Dog
Lupus familis
XP_542145
223
23905
I205
V
Q
D
V
N
V
A
I
T
M
C
V
L
G
L
Cat
Felis silvestris
Mouse
Mus musculus
P50172
292
32345
R273
I
L
L
G
N
P
G
R
K
I
M
E
F
F
S
Rat
Rattus norvegicus
P16232
288
31865
R270
L
L
G
N
P
G
R
R
I
M
E
F
L
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510050
476
52232
D283
E
T
K
L
R
E
F
D
P
E
A
L
D
L
R
Chicken
Gallus gallus
Q6PUF4
287
31460
W269
L
Q
P
V
H
G
L
W
V
L
L
P
N
P
R
Frog
Xenopus laevis
Q7SYS6
291
31577
F273
F
V
L
L
R
D
W
F
P
G
L
V
A
K
I
Zebra Danio
Brachydanio rerio
Q6PUF3
287
31899
D269
F
Y
A
T
L
F
R
D
W
F
P
Y
L
R
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y140
326
35725
C303
A
Y
Y
L
R
H
L
C
P
S
L
Y
F
W
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93
37.7
64.7
N.A.
36.5
36.1
N.A.
28.7
46.9
36.1
42.2
N.A.
24.8
N.A.
N.A.
N.A.
Protein Similarity:
100
94.2
51.7
67.6
N.A.
53.9
52.3
N.A.
42.4
58.7
55.2
60.3
N.A.
40.4
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
6.6
N.A.
0
6.6
N.A.
0
0
0
0
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
6.6
N.A.
13.3
13.3
N.A.
26.6
0
13.3
6.6
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
0
0
10
0
0
0
10
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
10
10
0
0
10
0
0
0
0
% C
% Asp:
0
0
10
0
0
10
0
19
0
0
0
19
10
0
10
% D
% Glu:
10
0
0
0
0
10
0
0
19
10
10
19
0
0
0
% E
% Phe:
19
0
0
0
0
10
10
10
0
10
0
10
28
10
0
% F
% Gly:
0
0
10
10
0
19
10
0
0
10
0
0
19
10
0
% G
% His:
0
0
0
0
10
10
0
0
0
0
0
0
0
19
0
% H
% Ile:
10
0
0
0
0
0
0
10
10
19
0
0
0
0
19
% I
% Lys:
0
0
10
0
19
0
19
0
19
19
0
0
0
10
0
% K
% Leu:
28
28
19
28
10
0
19
0
0
10
37
10
28
19
37
% L
% Met:
0
0
10
0
0
0
0
0
0
19
10
0
0
0
0
% M
% Asn:
0
0
0
10
28
0
0
0
0
0
19
0
10
0
0
% N
% Pro:
0
0
10
0
10
19
0
0
28
0
10
10
0
10
0
% P
% Gln:
0
19
0
19
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
19
10
28
0
19
28
0
0
0
0
0
10
19
% R
% Ser:
19
19
0
0
0
19
0
0
0
10
0
0
0
10
10
% S
% Thr:
0
10
0
10
0
0
0
19
10
0
0
0
0
0
0
% T
% Val:
10
10
0
19
0
10
0
0
10
0
0
19
0
0
0
% V
% Trp:
0
0
0
0
0
0
10
10
10
0
0
0
0
10
0
% W
% Tyr:
0
19
10
0
0
0
0
0
0
0
0
19
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _