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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IRF2BP2
All Species:
6.06
Human Site:
S175
Identified Species:
14.81
UniProt:
Q7Z5L9
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z5L9
NP_001070865.1
587
61025
S175
P
P
E
L
N
R
Q
S
P
N
P
R
R
G
H
Chimpanzee
Pan troglodytes
XP_525097
564
58580
T164
R
G
H
A
V
P
P
T
L
V
P
L
M
N
G
Rhesus Macaque
Macaca mulatta
Q2MJS2
794
82427
V268
N
G
P
A
S
A
A
V
L
P
P
P
P
P
H
Dog
Lupus familis
XP_849441
778
80777
S378
P
P
E
L
N
R
Q
S
P
N
P
R
R
G
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8K3X4
775
80546
V250
N
G
P
A
S
A
A
V
L
P
P
P
H
G
L
Rat
Rattus norvegicus
Q5EIC4
783
81477
V258
N
G
P
A
S
A
A
V
L
P
P
P
H
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519945
226
23147
Chicken
Gallus gallus
Frog
Xenopus laevis
Q7ZXS3
537
57226
P149
Q
V
N
G
I
L
L
P
N
G
F
P
K
P
E
Zebra Danio
Brachydanio rerio
Q6NZT6
491
52870
R103
R
Y
P
L
S
S
E
R
P
P
R
L
G
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784488
661
71839
T197
A
V
F
T
P
R
H
T
V
A
P
S
A
A
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.7
44
67.4
N.A.
44.9
44.3
N.A.
32.8
N.A.
62.5
56.7
N.A.
N.A.
N.A.
N.A.
32.9
Protein Similarity:
100
95.7
52.2
68.5
N.A.
53
52.4
N.A.
34
N.A.
70.1
66.4
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Identity:
100
6.6
13.3
100
N.A.
13.3
13.3
N.A.
0
N.A.
0
13.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
13.3
20
100
N.A.
20
20
N.A.
0
N.A.
6.6
26.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
40
0
30
30
0
0
10
0
0
10
20
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
20
0
0
0
10
0
0
0
0
0
0
0
20
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
40
0
10
0
0
0
0
0
10
0
0
10
40
20
% G
% His:
0
0
10
0
0
0
10
0
0
0
0
0
20
0
30
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% K
% Leu:
0
0
0
30
0
10
10
0
40
0
0
20
0
0
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
30
0
10
0
20
0
0
0
10
20
0
0
0
10
0
% N
% Pro:
20
20
40
0
10
10
10
10
30
40
70
40
10
20
0
% P
% Gln:
10
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% Q
% Arg:
20
0
0
0
0
30
0
10
0
0
10
20
20
0
0
% R
% Ser:
0
0
0
0
40
10
0
20
0
0
0
10
0
0
0
% S
% Thr:
0
0
0
10
0
0
0
20
0
0
0
0
0
0
0
% T
% Val:
0
20
0
0
10
0
0
30
10
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _