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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IRF2BP2
All Species:
4.55
Human Site:
S272
Identified Species:
11.11
UniProt:
Q7Z5L9
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z5L9
NP_001070865.1
587
61025
S272
A
H
R
G
P
A
D
S
L
S
T
A
A
G
A
Chimpanzee
Pan troglodytes
XP_525097
564
58580
S249
A
H
R
G
P
A
D
S
L
S
T
A
A
G
A
Rhesus Macaque
Macaca mulatta
Q2MJS2
794
82427
V428
Y
P
T
G
S
G
N
V
Y
S
S
A
S
G
V
Dog
Lupus familis
XP_849441
778
80777
Q463
E
A
V
A
K
E
K
Q
P
P
P
P
P
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8K3X4
775
80546
V409
Y
P
T
G
S
G
N
V
Y
S
S
A
S
G
V
Rat
Rattus norvegicus
Q5EIC4
783
81477
V417
Y
P
T
G
S
G
N
V
Y
S
S
A
S
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519945
226
23147
Chicken
Gallus gallus
Frog
Xenopus laevis
Q7ZXS3
537
57226
R233
H
D
G
K
E
K
H
R
A
D
S
Y
S
E
L
Zebra Danio
Brachydanio rerio
Q6NZT6
491
52870
E187
P
A
S
V
S
S
T
E
H
D
K
D
K
H
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784488
661
71839
Q324
S
A
S
G
V
A
K
Q
M
Y
Q
D
C
V
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.7
44
67.4
N.A.
44.9
44.3
N.A.
32.8
N.A.
62.5
56.7
N.A.
N.A.
N.A.
N.A.
32.9
Protein Similarity:
100
95.7
52.2
68.5
N.A.
53
52.4
N.A.
34
N.A.
70.1
66.4
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Identity:
100
100
26.6
0
N.A.
26.6
26.6
N.A.
0
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
46.6
0
N.A.
46.6
46.6
N.A.
0
N.A.
13.3
6.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
30
0
10
0
30
0
0
10
0
0
50
20
0
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
10
0
0
0
0
20
0
0
20
0
20
0
0
0
% D
% Glu:
10
0
0
0
10
10
0
10
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
60
0
30
0
0
0
0
0
0
0
50
0
% G
% His:
10
20
0
0
0
0
10
0
10
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
10
10
20
0
0
0
10
0
10
0
10
% K
% Leu:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
30
0
0
0
0
0
0
0
0
% N
% Pro:
10
30
0
0
20
0
0
0
10
10
10
10
10
10
10
% P
% Gln:
0
0
0
0
0
0
0
20
0
0
10
0
0
0
0
% Q
% Arg:
0
0
20
0
0
0
0
10
0
0
0
0
0
0
10
% R
% Ser:
10
0
20
0
40
10
0
20
0
50
40
0
40
0
0
% S
% Thr:
0
0
30
0
0
0
10
0
0
0
20
0
0
0
0
% T
% Val:
0
0
10
10
10
0
0
30
0
0
0
0
0
10
30
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
30
0
0
0
0
0
0
0
30
10
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _