Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABHD12B All Species: 17.27
Human Site: S40 Identified Species: 29.23
UniProt: Q7Z5M8 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z5M8 NP_853511.2 362 40776 S40 N L R Y F P H S C S M L G R K
Chimpanzee Pan troglodytes XP_522850 362 40684 S40 N L R Y F P H S C S M L G R K
Rhesus Macaque Macaca mulatta XP_001102076 362 40830 S40 N L R S F P H S C S T L G R K
Dog Lupus familis XP_853408 370 41828 S48 K G P S F P H S C S T L G R K
Cat Felis silvestris
Mouse Mus musculus Q99LR1 398 45251 L68 A L G R R K S L W F R L R K I
Rat Rattus norvegicus Q6AYT7 398 45277 L68 A L G R R K S L W F R L R K I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515209 427 47963 S105 P G R S F S C S L P K L R R K
Chicken Gallus gallus Q5ZIN0 381 43837 L51 P L G R R H G L W F R L R R L
Frog Xenopus laevis Q6IRP4 336 38243 Y40 L I L T F N M Y G G V I L L L
Zebra Danio Brachydanio rerio Q08C93 382 43267 L62 M W R L R R I L I W L L G I Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_725856 411 47343 S56 L P L I F R Y S V T F Q R G I
Honey Bee Apis mellifera XP_395396 359 41457 Y37 M K V S I F T Y L V I F G L L
Nematode Worm Caenorhab. elegans NP_505054 345 39613 T38 V Y F L P R Y T Q F I F F L N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P42840 284 32290
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 95 79.7 N.A. 39.2 39.4 N.A. 59.4 38 21.5 36.9 N.A. 27.4 29.8 27.8 N.A.
Protein Similarity: 100 99.7 96.6 86.7 N.A. 56.2 56.5 N.A. 70.2 56.6 39.7 57.5 N.A. 45.2 52.4 47.5 N.A.
P-Site Identity: 100 100 86.6 66.6 N.A. 13.3 13.3 N.A. 40 20 6.6 20 N.A. 13.3 6.6 0 N.A.
P-Site Similarity: 100 100 86.6 66.6 N.A. 20 20 N.A. 40 20 26.6 26.6 N.A. 26.6 13.3 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 37 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 8 0 29 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 8 0 50 8 0 0 0 29 8 15 8 0 0 % F
% Gly: 0 15 22 0 0 0 8 0 8 8 0 0 43 8 0 % G
% His: 0 0 0 0 0 8 29 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 8 8 0 8 0 8 0 15 8 0 8 22 % I
% Lys: 8 8 0 0 0 15 0 0 0 0 8 0 0 15 36 % K
% Leu: 15 43 15 15 0 0 0 29 15 0 8 65 8 22 22 % L
% Met: 15 0 0 0 0 0 8 0 0 0 15 0 0 0 0 % M
% Asn: 22 0 0 0 0 8 0 0 0 0 0 0 0 0 8 % N
% Pro: 15 8 8 0 8 29 0 0 0 8 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 8 0 0 8 0 0 0 % Q
% Arg: 0 0 36 22 29 22 0 0 0 0 22 0 36 43 0 % R
% Ser: 0 0 0 29 0 8 15 43 0 29 0 0 0 0 0 % S
% Thr: 0 0 0 8 0 0 8 8 0 8 15 0 0 0 0 % T
% Val: 8 0 8 0 0 0 0 0 8 8 8 0 0 0 0 % V
% Trp: 0 8 0 0 0 0 0 0 22 8 0 0 0 0 0 % W
% Tyr: 0 8 0 15 0 0 15 15 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _