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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABHD12B
All Species:
17.88
Human Site:
T183
Identified Species:
30.26
UniProt:
Q7Z5M8
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z5M8
NP_853511.2
362
40776
T183
Y
R
G
F
G
D
S
T
G
K
P
T
E
E
G
Chimpanzee
Pan troglodytes
XP_522850
362
40684
T183
Y
R
G
F
G
D
S
T
G
K
P
T
E
E
G
Rhesus Macaque
Macaca mulatta
XP_001102076
362
40830
T183
Y
R
G
F
G
D
S
T
G
K
P
T
E
E
G
Dog
Lupus familis
XP_853408
370
41828
T191
Y
R
G
F
G
D
S
T
G
K
P
T
E
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q99LR1
398
45251
V212
Y
R
G
W
G
D
S
V
G
T
P
S
E
R
G
Rat
Rattus norvegicus
Q6AYT7
398
45277
V212
Y
R
G
W
G
D
S
V
G
T
P
S
E
R
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515209
427
47963
T248
Y
R
G
F
G
D
S
T
G
S
P
T
E
E
G
Chicken
Gallus gallus
Q5ZIN0
381
43837
V195
Y
R
G
W
G
D
S
V
G
S
P
S
E
R
G
Frog
Xenopus laevis
Q6IRP4
336
38243
R179
V
L
D
Y
V
M
T
R
P
D
I
D
K
T
K
Zebra Danio
Brachydanio rerio
Q08C93
382
43267
E198
Y
R
G
W
G
D
S
E
G
S
P
S
E
R
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_725856
411
47343
D225
Y
R
G
Y
A
D
S
D
P
V
P
P
T
E
E
Honey Bee
Apis mellifera
XP_395396
359
41457
A173
G
Y
G
D
S
E
E
A
E
L
S
E
M
G
V
Nematode Worm
Caenorhab. elegans
NP_505054
345
39613
E174
E
D
T
K
T
V
Y
E
W
L
K
E
N
C
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P42840
284
32290
G128
E
G
S
P
S
E
K
G
L
K
L
D
A
D
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95
79.7
N.A.
39.2
39.4
N.A.
59.4
38
21.5
36.9
N.A.
27.4
29.8
27.8
N.A.
Protein Similarity:
100
99.7
96.6
86.7
N.A.
56.2
56.5
N.A.
70.2
56.6
39.7
57.5
N.A.
45.2
52.4
47.5
N.A.
P-Site Identity:
100
100
100
100
N.A.
66.6
66.6
N.A.
93.3
66.6
0
66.6
N.A.
46.6
6.6
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
80
80
N.A.
93.3
80
20
80
N.A.
53.3
13.3
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
8
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% C
% Asp:
0
8
8
8
0
72
0
8
0
8
0
15
0
8
0
% D
% Glu:
15
0
0
0
0
15
8
15
8
0
0
15
65
43
8
% E
% Phe:
0
0
0
36
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
79
0
65
0
0
8
65
0
0
0
0
8
72
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% I
% Lys:
0
0
0
8
0
0
8
0
0
36
8
0
8
0
8
% K
% Leu:
0
8
0
0
0
0
0
0
8
15
8
0
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
15
0
72
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
72
0
0
0
0
0
8
0
0
0
0
0
29
0
% R
% Ser:
0
0
8
0
15
0
72
0
0
22
8
29
0
0
0
% S
% Thr:
0
0
8
0
8
0
8
36
0
15
0
36
8
8
0
% T
% Val:
8
0
0
0
8
8
0
22
0
8
0
0
0
0
8
% V
% Trp:
0
0
0
29
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
72
8
0
15
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _