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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABHD12B
All Species:
17.58
Human Site:
T306
Identified Species:
29.74
UniProt:
Q7Z5M8
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z5M8
NP_853511.2
362
40776
T306
L
H
G
E
D
D
R
T
V
P
L
E
Y
G
K
Chimpanzee
Pan troglodytes
XP_522850
362
40684
T306
L
H
G
E
D
D
R
T
V
P
L
E
Y
G
K
Rhesus Macaque
Macaca mulatta
XP_001102076
362
40830
T306
L
H
G
E
D
D
R
T
V
P
L
E
Y
G
K
Dog
Lupus familis
XP_853408
370
41828
T314
I
H
G
E
D
D
N
T
V
P
L
E
F
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q99LR1
398
45251
V335
L
H
A
E
D
D
P
V
V
P
F
H
L
G
R
Rat
Rattus norvegicus
Q6AYT7
398
45277
V335
L
H
A
E
D
D
P
V
V
P
F
H
L
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515209
427
47963
T371
L
H
G
E
D
D
K
T
V
P
L
E
Q
G
K
Chicken
Gallus gallus
Q5ZIN0
381
43837
V318
L
H
A
E
D
D
P
V
V
P
F
H
L
G
K
Frog
Xenopus laevis
Q6IRP4
336
38243
R289
L
S
P
S
R
T
K
R
L
A
I
F
P
D
G
Zebra Danio
Brachydanio rerio
Q08C93
382
43267
V321
L
H
A
E
D
D
T
V
V
P
F
Q
L
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_725856
411
47343
V349
I
H
A
E
D
D
V
V
V
P
F
N
L
G
Y
Honey Bee
Apis mellifera
XP_395396
359
41457
I296
L
H
A
E
D
D
N
I
I
P
F
A
L
G
E
Nematode Worm
Caenorhab. elegans
NP_505054
345
39613
I282
L
H
A
E
D
D
K
I
L
P
V
K
L
G
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P42840
284
32290
P236
L
K
D
E
I
V
P
P
F
H
M
R
K
L
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95
79.7
N.A.
39.2
39.4
N.A.
59.4
38
21.5
36.9
N.A.
27.4
29.8
27.8
N.A.
Protein Similarity:
100
99.7
96.6
86.7
N.A.
56.2
56.5
N.A.
70.2
56.6
39.7
57.5
N.A.
45.2
52.4
47.5
N.A.
P-Site Identity:
100
100
100
80
N.A.
53.3
53.3
N.A.
86.6
60
6.6
60
N.A.
46.6
46.6
46.6
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
60
60
N.A.
93.3
60
26.6
66.6
N.A.
53.3
60
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
50
0
0
0
0
0
0
8
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
86
86
0
0
0
0
0
0
0
8
0
% D
% Glu:
0
0
0
93
0
0
0
0
0
0
0
36
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
43
8
8
0
0
% F
% Gly:
0
0
36
0
0
0
0
0
0
0
0
0
0
86
8
% G
% His:
0
86
0
0
0
0
0
0
0
8
0
22
0
0
0
% H
% Ile:
15
0
0
0
8
0
0
15
8
0
8
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
22
0
0
0
0
8
8
0
50
% K
% Leu:
86
0
0
0
0
0
0
0
15
0
36
0
50
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
15
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
8
0
0
0
29
8
0
86
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% Q
% Arg:
0
0
0
0
8
0
22
8
0
0
0
8
0
0
22
% R
% Ser:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
8
8
36
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
8
8
36
72
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
22
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _