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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABHD12B All Species: 14.55
Human Site: T56 Identified Species: 24.62
UniProt: Q7Z5M8 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z5M8 NP_853511.2 362 40776 T56 A A L Y D S F T S K S L K E H
Chimpanzee Pan troglodytes XP_522850 362 40684 T56 A A L Y D S F T S K S L K E H
Rhesus Macaque Macaca mulatta XP_001102076 362 40830 T56 A A L Y D S F T S K S L K E H
Dog Lupus familis XP_853408 370 41828 T64 A S L Y H S F T S K P L K E H
Cat Felis silvestris
Mouse Mus musculus Q99LR1 398 45251 I84 L C V L G F Y I A I P F L V K
Rat Rattus norvegicus Q6AYT7 398 45277 I84 L C V L G F Y I A I P F L V K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515209 427 47963 I121 V T L Y E T L I N K S L K E R
Chicken Gallus gallus Q5ZIN0 381 43837 I67 I W L L G V Y I A I P F L V K
Frog Xenopus laevis Q6IRP4 336 38243 I56 I F V S I A G I L F K F Q D V
Zebra Danio Brachydanio rerio Q08C93 382 43267 V78 A I P V I I K V C P S I Q A K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_725856 411 47343 P72 F L T F I K Y P K G L D L T K
Honey Bee Apis mellifera XP_395396 359 41457 A53 I I F H Y S Y A F Q K K I L F
Nematode Worm Caenorhab. elegans NP_505054 345 39613 Y54 R R L P N T D Y N D L A S N N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P42840 284 32290 M8 M L W K V S K M F L G G L V A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 95 79.7 N.A. 39.2 39.4 N.A. 59.4 38 21.5 36.9 N.A. 27.4 29.8 27.8 N.A.
Protein Similarity: 100 99.7 96.6 86.7 N.A. 56.2 56.5 N.A. 70.2 56.6 39.7 57.5 N.A. 45.2 52.4 47.5 N.A.
P-Site Identity: 100 100 100 80 N.A. 0 0 N.A. 46.6 6.6 0 13.3 N.A. 0 6.6 6.6 N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 20 20 N.A. 66.6 20 26.6 26.6 N.A. 13.3 26.6 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 37 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 36 22 0 0 0 8 0 8 22 0 0 8 0 8 8 % A
% Cys: 0 15 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 22 0 8 0 0 8 0 8 0 8 0 % D
% Glu: 0 0 0 0 8 0 0 0 0 0 0 0 0 36 0 % E
% Phe: 8 8 8 8 0 15 29 0 15 8 0 29 0 0 8 % F
% Gly: 0 0 0 0 22 0 8 0 0 8 8 8 0 0 0 % G
% His: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 29 % H
% Ile: 22 15 0 0 22 8 0 36 0 22 0 8 8 0 0 % I
% Lys: 0 0 0 8 0 8 15 0 8 36 15 8 36 0 36 % K
% Leu: 15 15 50 22 0 0 8 0 8 8 15 36 36 8 0 % L
% Met: 8 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 0 0 15 0 0 0 0 8 8 % N
% Pro: 0 0 8 8 0 0 0 8 0 8 29 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 8 0 0 15 0 0 % Q
% Arg: 8 8 0 0 0 0 0 0 0 0 0 0 0 0 8 % R
% Ser: 0 8 0 8 0 43 0 0 29 0 36 0 8 0 0 % S
% Thr: 0 8 8 0 0 15 0 29 0 0 0 0 0 8 0 % T
% Val: 8 0 22 8 8 8 0 8 0 0 0 0 0 29 8 % V
% Trp: 0 8 8 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 36 8 0 36 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _