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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABHD12B
All Species:
16.67
Human Site:
Y52
Identified Species:
28.21
UniProt:
Q7Z5M8
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z5M8
NP_853511.2
362
40776
Y52
G
R
K
I
A
A
L
Y
D
S
F
T
S
K
S
Chimpanzee
Pan troglodytes
XP_522850
362
40684
Y52
G
R
K
I
A
A
L
Y
D
S
F
T
S
K
S
Rhesus Macaque
Macaca mulatta
XP_001102076
362
40830
Y52
G
R
K
I
A
A
L
Y
D
S
F
T
S
K
S
Dog
Lupus familis
XP_853408
370
41828
Y60
G
R
K
I
A
S
L
Y
H
S
F
T
S
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q99LR1
398
45251
L80
R
K
I
L
L
C
V
L
G
F
Y
I
A
I
P
Rat
Rattus norvegicus
Q6AYT7
398
45277
L80
R
K
I
L
L
C
V
L
G
F
Y
I
A
I
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515209
427
47963
Y117
R
R
K
F
V
T
L
Y
E
T
L
I
N
K
S
Chicken
Gallus gallus
Q5ZIN0
381
43837
L63
R
R
L
I
I
W
L
L
G
V
Y
I
A
I
P
Frog
Xenopus laevis
Q6IRP4
336
38243
S52
L
L
L
L
I
F
V
S
I
A
G
I
L
F
K
Zebra Danio
Brachydanio rerio
Q08C93
382
43267
V74
G
I
Y
I
A
I
P
V
I
I
K
V
C
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_725856
411
47343
F68
R
G
I
L
F
L
T
F
I
K
Y
P
K
G
L
Honey Bee
Apis mellifera
XP_395396
359
41457
H49
G
L
L
P
I
I
F
H
Y
S
Y
A
F
Q
K
Nematode Worm
Caenorhab. elegans
NP_505054
345
39613
P50
F
L
N
F
R
R
L
P
N
T
D
Y
N
D
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P42840
284
32290
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95
79.7
N.A.
39.2
39.4
N.A.
59.4
38
21.5
36.9
N.A.
27.4
29.8
27.8
N.A.
Protein Similarity:
100
99.7
96.6
86.7
N.A.
56.2
56.5
N.A.
70.2
56.6
39.7
57.5
N.A.
45.2
52.4
47.5
N.A.
P-Site Identity:
100
100
100
80
N.A.
0
0
N.A.
40
20
0
26.6
N.A.
0
13.3
6.6
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
33.3
33.3
N.A.
60
33.3
20
26.6
N.A.
20
33.3
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
36
22
0
0
0
8
0
8
22
0
0
% A
% Cys:
0
0
0
0
0
15
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
22
0
8
0
0
8
0
% D
% Glu:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% E
% Phe:
8
0
0
15
8
8
8
8
0
15
29
0
8
8
0
% F
% Gly:
43
8
0
0
0
0
0
0
22
0
8
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% H
% Ile:
0
8
22
43
22
15
0
0
22
8
0
36
0
22
0
% I
% Lys:
0
15
36
0
0
0
0
0
0
8
8
0
8
36
15
% K
% Leu:
8
22
22
29
15
8
50
22
0
0
8
0
8
0
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
8
0
0
0
15
0
0
% N
% Pro:
0
0
0
8
0
0
8
8
0
0
0
8
0
8
29
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
36
43
0
0
8
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
8
0
8
0
36
0
0
29
0
36
% S
% Thr:
0
0
0
0
0
8
8
0
0
15
0
29
0
0
0
% T
% Val:
0
0
0
0
8
0
22
8
0
8
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
36
8
0
36
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _