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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDK1
All Species:
12.73
Human Site:
S1218
Identified Species:
21.54
UniProt:
Q7Z5N4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z5N4
NP_689957.3
2213
242076
S1218
Y
R
I
K
Y
W
R
S
D
L
Q
S
S
A
V
Chimpanzee
Pan troglodytes
XP_518946
2168
238269
S1173
Y
R
I
K
Y
W
R
S
D
L
Q
S
S
A
V
Rhesus Macaque
Macaca mulatta
XP_001105243
2118
232418
S1152
Q
Y
N
G
N
P
E
S
V
G
Y
R
I
K
Y
Dog
Lupus familis
XP_547004
2144
235913
E1170
I
N
D
R
L
E
R
E
F
T
I
E
G
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q3UH53
2193
240287
S1200
Y
R
V
K
Y
W
R
S
D
Q
P
S
S
A
L
Rat
Rattus norvegicus
XP_001073292
2181
239558
S1188
Y
R
V
K
Y
W
R
S
D
Q
P
S
S
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513017
2131
235273
Q1167
E
W
T
E
Y
E
L
Q
I
Q
A
F
N
A
I
Chicken
Gallus gallus
Q8AV58
2169
239459
V1170
Y
R
I
K
F
W
R
V
D
L
Q
P
S
A
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_686686
2126
234665
I1163
W
T
E
Y
Q
L
Q
I
Q
A
F
N
S
I
G
Tiger Blowfish
Takifugu rubipres
Q98902
1277
141937
Q314
D
M
F
D
R
R
L
Q
F
T
N
I
S
E
S
Fruit Fly
Dros. melanogaster
O97394
2224
246236
K1211
I
S
Y
K
Q
L
V
K
T
P
G
T
I
K
Y
Honey Bee
Apis mellifera
XP_623565
2176
242722
V1173
Y
N
V
T
Y
T
E
V
R
T
K
K
S
K
S
Nematode Worm
Caenorhab. elegans
Q9N3X8
2325
259146
D1201
I
V
Y
R
E
I
D
D
E
N
W
K
E
V
R
Sea Urchin
Strong. purpuratus
XP_781559
2931
322437
G1509
F
Q
F
R
Q
L
P
G
G
S
F
M
E
E
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.7
91.5
86.7
N.A.
89.7
87.3
N.A.
79.6
78.9
N.A.
66
20.5
36.3
36.3
26.1
20.7
Protein Similarity:
100
96.1
93
91.5
N.A.
94
92
N.A.
87.8
87.8
N.A.
79.8
33.5
53.5
53.5
43.8
37.1
P-Site Identity:
100
100
6.6
6.6
N.A.
73.3
73.3
N.A.
13.3
73.3
N.A.
6.6
6.6
6.6
20
0
0
P-Site Similarity:
100
100
6.6
13.3
N.A.
86.6
86.6
N.A.
33.3
86.6
N.A.
26.6
6.6
13.3
33.3
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
8
8
0
0
43
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
8
0
0
8
8
36
0
0
0
0
0
0
% D
% Glu:
8
0
8
8
8
15
15
8
8
0
0
8
15
15
8
% E
% Phe:
8
0
15
0
8
0
0
0
15
0
15
8
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
8
8
8
8
0
8
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
22
0
22
0
0
8
0
8
8
0
8
8
15
8
8
% I
% Lys:
0
0
0
43
0
0
0
8
0
0
8
15
0
22
0
% K
% Leu:
0
0
0
0
8
22
15
0
0
22
0
0
0
8
22
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
15
8
0
8
0
0
0
0
8
8
8
8
0
0
% N
% Pro:
0
0
0
0
0
8
8
0
0
8
15
8
0
0
0
% P
% Gln:
8
8
0
0
22
0
8
15
8
22
22
0
0
0
0
% Q
% Arg:
0
36
0
22
8
8
43
0
8
0
0
8
0
0
8
% R
% Ser:
0
8
0
0
0
0
0
36
0
8
0
29
58
0
15
% S
% Thr:
0
8
8
8
0
8
0
0
8
22
0
8
0
0
8
% T
% Val:
0
8
22
0
0
0
8
15
8
0
0
0
0
8
15
% V
% Trp:
8
8
0
0
0
36
0
0
0
0
8
0
0
0
0
% W
% Tyr:
43
8
15
8
43
0
0
0
0
0
8
0
0
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _