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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDK1
All Species:
24.24
Human Site:
S1770
Identified Species:
41.03
UniProt:
Q7Z5N4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z5N4
NP_689957.3
2213
242076
S1770
V
R
L
K
N
L
T
S
H
T
K
Y
L
V
S
Chimpanzee
Pan troglodytes
XP_518946
2168
238269
S1725
V
R
L
K
N
L
T
S
H
T
K
Y
L
V
S
Rhesus Macaque
Macaca mulatta
XP_001105243
2118
232418
Y1681
Q
N
G
N
I
Q
G
Y
K
I
Y
Y
W
E
A
Dog
Lupus familis
XP_547004
2144
235913
S1704
V
K
L
K
N
L
T
S
H
T
Q
Y
L
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q3UH53
2193
240287
S1752
V
K
I
K
D
L
T
S
H
T
K
Y
L
I
S
Rat
Rattus norvegicus
XP_001073292
2181
239558
S1740
V
K
I
K
D
L
T
S
H
T
K
Y
L
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513017
2131
235273
F1695
Y
L
V
S
I
S
A
F
N
A
A
G
D
G
P
Chicken
Gallus gallus
Q8AV58
2169
239459
S1722
S
A
S
K
N
L
T
S
H
T
R
Y
L
V
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_686686
2126
234665
N1691
M
V
K
L
L
A
F
N
A
A
G
D
G
P
F
Tiger Blowfish
Takifugu rubipres
Q98902
1277
141937
T842
V
L
L
E
N
S
T
T
I
R
V
T
W
S
A
Fruit Fly
Dros. melanogaster
O97394
2224
246236
K1755
H
S
L
V
F
L
D
K
F
T
E
Y
R
I
Q
Honey Bee
Apis mellifera
XP_623565
2176
242722
K1710
H
S
L
V
F
L
D
K
Y
T
E
Y
R
I
Q
Nematode Worm
Caenorhab. elegans
Q9N3X8
2325
259146
L1780
K
P
G
P
V
G
I
L
R
F
S
D
V
L
M
Sea Urchin
Strong. purpuratus
XP_781559
2931
322437
R2137
A
K
M
Q
P
G
S
R
A
P
V
H
G
F
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.7
91.5
86.7
N.A.
89.7
87.3
N.A.
79.6
78.9
N.A.
66
20.5
36.3
36.3
26.1
20.7
Protein Similarity:
100
96.1
93
91.5
N.A.
94
92
N.A.
87.8
87.8
N.A.
79.8
33.5
53.5
53.5
43.8
37.1
P-Site Identity:
100
100
6.6
86.6
N.A.
73.3
80
N.A.
0
66.6
N.A.
0
26.6
26.6
26.6
0
6.6
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
13.3
73.3
N.A.
13.3
46.6
40
46.6
13.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
8
8
0
15
15
8
0
0
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
15
0
15
0
0
0
0
15
8
0
0
% D
% Glu:
0
0
0
8
0
0
0
0
0
0
15
0
0
8
0
% E
% Phe:
0
0
0
0
15
0
8
8
8
8
0
0
0
8
8
% F
% Gly:
0
0
15
0
0
15
8
0
0
0
8
8
15
8
0
% G
% His:
15
0
0
0
0
0
0
0
43
0
0
8
0
0
0
% H
% Ile:
0
0
15
0
15
0
8
0
8
8
0
0
0
22
0
% I
% Lys:
8
29
8
43
0
0
0
15
8
0
29
0
0
0
0
% K
% Leu:
0
15
43
8
8
58
0
8
0
0
0
0
43
8
0
% L
% Met:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
8
0
8
36
0
0
8
8
0
0
0
0
0
0
% N
% Pro:
0
8
0
8
8
0
0
0
0
8
0
0
0
8
8
% P
% Gln:
8
0
0
8
0
8
0
0
0
0
8
0
0
0
15
% Q
% Arg:
0
15
0
0
0
0
0
8
8
8
8
0
15
0
0
% R
% Ser:
8
15
8
8
0
15
8
43
0
0
8
0
0
8
43
% S
% Thr:
0
0
0
0
0
0
50
8
0
58
0
8
0
0
0
% T
% Val:
43
8
8
15
8
0
0
0
0
0
15
0
8
36
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% W
% Tyr:
8
0
0
0
0
0
0
8
8
0
8
65
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _