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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SDK1 All Species: 23.64
Human Site: S1942 Identified Species: 40
UniProt: Q7Z5N4 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.31
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z5N4 NP_689957.3 2213 242076 S1942 Y V I E A R P S D E G L W D M
Chimpanzee Pan troglodytes XP_518946 2168 238269 S1897 Y V I E A R P S D E G L W D M
Rhesus Macaque Macaca mulatta XP_001105243 2118 232418 R1851 E G S P G S P R D V L V T K S
Dog Lupus familis XP_547004 2144 235913 S1876 Y V I E A R P S D E G L W D M
Cat Felis silvestris
Mouse Mus musculus Q3UH53 2193 240287 S1924 Y V I E A R P S D E G L W D M
Rat Rattus norvegicus XP_001073292 2181 239558 S1912 Y V I E A R P S D E G L W D M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513017 2131 235273 V1865 E G L W D M F V K D I P R S A
Chicken Gallus gallus Q8AV58 2169 239459 S1894 Y I I E A R P S D E G L W D M
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_686686 2126 234665 R1861 G L W D T F V R H L P P T S T
Tiger Blowfish Takifugu rubipres Q98902 1277 141937 T1012 Q F L L M A R T A A G K G L S
Fruit Fly Dros. melanogaster O97394 2224 246236 R1925 Y L I E A K K R D D S R W T K
Honey Bee Apis mellifera XP_623565 2176 242722 R1889 S R W Q T I V R S S N G P L T
Nematode Worm Caenorhab. elegans Q9N3X8 2325 259146 G1954 T R P T H P I G E W I T L R P
Sea Urchin Strong. purpuratus XP_781559 2931 322437 W2401 F A K I A L D W A E G K I L Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.7 91.5 86.7 N.A. 89.7 87.3 N.A. 79.6 78.9 N.A. 66 20.5 36.3 36.3 26.1 20.7
Protein Similarity: 100 96.1 93 91.5 N.A. 94 92 N.A. 87.8 87.8 N.A. 79.8 33.5 53.5 53.5 43.8 37.1
P-Site Identity: 100 100 13.3 100 N.A. 100 100 N.A. 0 93.3 N.A. 0 6.6 40 0 0 20
P-Site Similarity: 100 100 20 100 N.A. 100 100 N.A. 13.3 100 N.A. 13.3 20 60 6.6 6.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 58 8 0 0 15 8 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 8 0 8 0 58 15 0 0 0 43 0 % D
% Glu: 15 0 0 50 0 0 0 0 8 50 0 0 0 0 0 % E
% Phe: 8 8 0 0 0 8 8 0 0 0 0 0 0 0 0 % F
% Gly: 8 15 0 0 8 0 0 8 0 0 58 8 8 0 0 % G
% His: 0 0 0 0 8 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 8 50 8 0 8 8 0 0 0 15 0 8 0 0 % I
% Lys: 0 0 8 0 0 8 8 0 8 0 0 15 0 8 8 % K
% Leu: 0 15 15 8 0 8 0 0 0 8 8 43 8 22 0 % L
% Met: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 43 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % N
% Pro: 0 0 8 8 0 8 50 0 0 0 8 15 8 0 8 % P
% Gln: 8 0 0 8 0 0 0 0 0 0 0 0 0 0 8 % Q
% Arg: 0 15 0 0 0 43 8 29 0 0 0 8 8 8 0 % R
% Ser: 8 0 8 0 0 8 0 43 8 8 8 0 0 15 15 % S
% Thr: 8 0 0 8 15 0 0 8 0 0 0 8 15 8 15 % T
% Val: 0 36 0 0 0 0 15 8 0 8 0 8 0 0 0 % V
% Trp: 0 0 15 8 0 0 0 8 0 8 0 0 50 0 0 % W
% Tyr: 50 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _