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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDK1
All Species:
17.27
Human Site:
S2124
Identified Species:
29.23
UniProt:
Q7Z5N4
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z5N4
NP_689957.3
2213
242076
S2124
K
E
K
S
A
D
A
S
E
S
E
A
T
D
S
Chimpanzee
Pan troglodytes
XP_518946
2168
238269
S2079
K
E
K
S
A
D
A
S
E
S
E
A
T
D
S
Rhesus Macaque
Macaca mulatta
XP_001105243
2118
232418
R2028
F
S
K
K
N
G
T
R
S
P
P
R
P
S
P
Dog
Lupus familis
XP_547004
2144
235913
V2055
A
N
L
K
E
K
S
V
D
A
S
E
S
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q3UH53
2193
240287
D2104
N
L
K
E
K
S
V
D
G
S
E
S
E
A
S
Rat
Rattus norvegicus
XP_001073292
2181
239558
D2092
N
L
K
E
K
S
V
D
G
S
E
S
E
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513017
2131
235273
T2043
N
A
S
E
S
E
A
T
D
S
D
Y
E
D
E
Chicken
Gallus gallus
Q8AV58
2169
239459
S2076
N
E
K
P
L
E
M
S
E
S
E
A
T
D
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_686686
2126
234665
T2038
E
M
S
E
S
E
A
T
D
S
E
C
E
E
E
Tiger Blowfish
Takifugu rubipres
Q98902
1277
141937
Y1189
K
D
E
T
F
G
E
Y
R
S
L
E
S
D
L
Fruit Fly
Dros. melanogaster
O97394
2224
246236
S2135
S
S
V
T
E
K
P
S
E
V
S
S
S
E
A
Honey Bee
Apis mellifera
XP_623565
2176
242722
L2071
Y
H
S
D
E
E
S
L
K
G
Y
D
E
N
P
Nematode Worm
Caenorhab. elegans
Q9N3X8
2325
259146
P2141
P
L
P
N
S
G
P
P
H
T
S
V
E
A
M
Sea Urchin
Strong. purpuratus
XP_781559
2931
322437
K2809
F
T
L
E
S
I
G
K
E
V
I
E
K
V
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.7
91.5
86.7
N.A.
89.7
87.3
N.A.
79.6
78.9
N.A.
66
20.5
36.3
36.3
26.1
20.7
Protein Similarity:
100
96.1
93
91.5
N.A.
94
92
N.A.
87.8
87.8
N.A.
79.8
33.5
53.5
53.5
43.8
37.1
P-Site Identity:
100
100
6.6
0
N.A.
26.6
26.6
N.A.
20
66.6
N.A.
20
20
13.3
0
0
6.6
P-Site Similarity:
100
100
6.6
33.3
N.A.
33.3
33.3
N.A.
53.3
73.3
N.A.
60
46.6
46.6
26.6
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
15
0
29
0
0
8
0
22
0
22
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
8
0
8
0
15
0
15
22
0
8
8
0
36
0
% D
% Glu:
8
22
8
36
22
29
8
0
36
0
43
22
43
22
15
% E
% Phe:
15
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
22
8
0
15
8
0
0
0
0
8
% G
% His:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% I
% Lys:
22
0
43
15
15
15
0
8
8
0
0
0
8
0
8
% K
% Leu:
0
22
15
0
8
0
0
8
0
0
8
0
0
0
8
% L
% Met:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
8
% M
% Asn:
29
8
0
8
8
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
8
0
8
8
0
0
15
8
0
8
8
0
8
0
15
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
8
0
0
8
0
0
0
% R
% Ser:
8
15
22
15
29
15
15
29
8
58
22
22
22
8
36
% S
% Thr:
0
8
0
15
0
0
8
15
0
8
0
0
22
0
0
% T
% Val:
0
0
8
0
0
0
15
8
0
15
0
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
8
0
0
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _