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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDK1
All Species:
12.42
Human Site:
S2131
Identified Species:
21.03
UniProt:
Q7Z5N4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z5N4
NP_689957.3
2213
242076
S2131
S
E
S
E
A
T
D
S
D
Y
E
D
A
L
P
Chimpanzee
Pan troglodytes
XP_518946
2168
238269
S2086
S
E
S
E
A
T
D
S
D
Y
E
D
A
L
P
Rhesus Macaque
Macaca mulatta
XP_001105243
2118
232418
P2035
R
S
P
P
R
P
S
P
G
G
L
H
Y
S
D
Dog
Lupus familis
XP_547004
2144
235913
G2062
V
D
A
S
E
S
E
G
T
D
S
E
S
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q3UH53
2193
240287
S2111
D
G
S
E
S
E
A
S
D
S
D
Y
E
E
A
Rat
Rattus norvegicus
XP_001073292
2181
239558
S2099
D
G
S
E
S
E
A
S
D
S
D
Y
E
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513017
2131
235273
E2050
T
D
S
D
Y
E
D
E
L
P
K
H
S
F
V
Chicken
Gallus gallus
Q8AV58
2169
239459
S2083
S
E
S
E
A
T
D
S
D
Y
E
D
E
L
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_686686
2126
234665
E2045
T
D
S
E
C
E
E
E
P
I
K
H
S
F
V
Tiger Blowfish
Takifugu rubipres
Q98902
1277
141937
L1196
Y
R
S
L
E
S
D
L
E
E
K
R
T
A
S
Fruit Fly
Dros. melanogaster
O97394
2224
246236
A2142
S
E
V
S
S
S
E
A
S
Q
H
S
E
S
E
Honey Bee
Apis mellifera
XP_623565
2176
242722
P2078
L
K
G
Y
D
E
N
P
D
D
S
S
V
T
E
Nematode Worm
Caenorhab. elegans
Q9N3X8
2325
259146
M2148
P
H
T
S
V
E
A
M
Q
K
L
S
A
L
V
Sea Urchin
Strong. purpuratus
XP_781559
2931
322437
K2816
K
E
V
I
E
K
V
K
Q
V
T
A
D
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.7
91.5
86.7
N.A.
89.7
87.3
N.A.
79.6
78.9
N.A.
66
20.5
36.3
36.3
26.1
20.7
Protein Similarity:
100
96.1
93
91.5
N.A.
94
92
N.A.
87.8
87.8
N.A.
79.8
33.5
53.5
53.5
43.8
37.1
P-Site Identity:
100
100
0
0
N.A.
26.6
26.6
N.A.
13.3
93.3
N.A.
13.3
13.3
13.3
6.6
13.3
13.3
P-Site Similarity:
100
100
0
40
N.A.
40
40
N.A.
46.6
93.3
N.A.
46.6
33.3
40
20
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
22
0
22
8
0
0
0
8
22
8
15
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
22
0
8
8
0
36
0
43
15
15
22
8
0
15
% D
% Glu:
0
36
0
43
22
43
22
15
8
8
22
8
29
22
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% F
% Gly:
0
15
8
0
0
0
0
8
8
8
0
0
0
0
8
% G
% His:
0
8
0
0
0
0
0
0
0
0
8
22
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
8
8
0
0
0
8
0
8
0
8
22
0
0
0
0
% K
% Leu:
8
0
0
8
0
0
0
8
8
0
15
0
0
36
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
8
8
0
8
0
15
8
8
0
0
0
0
22
% P
% Gln:
0
0
0
0
0
0
0
0
15
8
0
0
0
0
0
% Q
% Arg:
8
8
0
0
8
0
0
0
0
0
0
8
0
0
0
% R
% Ser:
29
8
58
22
22
22
8
36
8
15
15
22
22
15
8
% S
% Thr:
15
0
8
0
0
22
0
0
8
0
8
0
8
8
0
% T
% Val:
8
0
15
0
8
0
8
0
0
8
0
0
8
0
22
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
8
0
0
0
0
22
0
15
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _