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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDK1
All Species:
10.3
Human Site:
S354
Identified Species:
17.44
UniProt:
Q7Z5N4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z5N4
NP_689957.3
2213
242076
S354
L
T
I
S
N
P
T
S
A
D
T
G
P
Y
V
Chimpanzee
Pan troglodytes
XP_518946
2168
238269
Y315
T
S
A
D
T
G
P
Y
V
C
E
A
A
L
R
Rhesus Macaque
Macaca mulatta
XP_001105243
2118
232418
A299
T
I
S
N
P
T
S
A
D
T
G
L
Y
V
C
Dog
Lupus familis
XP_547004
2144
235913
E318
K
A
F
L
S
I
I
E
P
P
Y
F
T
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q3UH53
2193
240287
S336
L
T
I
T
N
P
T
S
A
D
T
G
M
Y
V
Rat
Rattus norvegicus
XP_001073292
2181
239558
S324
L
T
I
I
N
P
T
S
A
D
T
G
M
Y
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513017
2131
235273
E315
P
M
S
R
I
L
T
E
V
D
K
T
V
D
L
Chicken
Gallus gallus
Q8AV58
2169
239459
E315
D
V
G
M
Y
F
C
E
A
K
L
R
D
S
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_686686
2126
234665
V311
R
R
K
M
M
G
E
V
E
K
S
V
D
I
Q
Tiger Blowfish
Takifugu rubipres
Q98902
1277
141937
Fruit Fly
Dros. melanogaster
O97394
2224
246236
S329
A
L
L
Q
A
N
S
S
H
S
G
E
Y
T
C
Honey Bee
Apis mellifera
XP_623565
2176
242722
S315
S
C
H
V
D
L
R
S
G
E
Y
P
T
M
N
Nematode Worm
Caenorhab. elegans
Q9N3X8
2325
259146
N331
P
I
L
K
D
L
P
N
E
I
Q
K
T
V
G
Sea Urchin
Strong. purpuratus
XP_781559
2931
322437
E352
E
P
N
K
S
P
L
E
R
I
I
Q
E
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.7
91.5
86.7
N.A.
89.7
87.3
N.A.
79.6
78.9
N.A.
66
20.5
36.3
36.3
26.1
20.7
Protein Similarity:
100
96.1
93
91.5
N.A.
94
92
N.A.
87.8
87.8
N.A.
79.8
33.5
53.5
53.5
43.8
37.1
P-Site Identity:
100
0
0
0
N.A.
86.6
86.6
N.A.
13.3
6.6
N.A.
0
0
6.6
6.6
0
6.6
P-Site Similarity:
100
6.6
20
6.6
N.A.
93.3
86.6
N.A.
20
6.6
N.A.
6.6
0
20
20
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
8
0
0
8
29
0
0
8
8
15
8
% A
% Cys:
0
8
0
0
0
0
8
0
0
8
0
0
0
0
15
% C
% Asp:
8
0
0
8
15
0
0
0
8
29
0
0
15
8
0
% D
% Glu:
8
0
0
0
0
0
8
29
15
8
8
8
8
0
8
% E
% Phe:
0
0
8
0
0
8
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
8
0
0
15
0
0
8
0
15
22
0
0
8
% G
% His:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
15
22
8
8
8
8
0
0
15
8
0
0
8
0
% I
% Lys:
8
0
8
15
0
0
0
0
0
15
8
8
0
0
0
% K
% Leu:
22
8
15
8
0
22
8
0
0
0
8
8
0
8
8
% L
% Met:
0
8
0
15
8
0
0
0
0
0
0
0
15
8
0
% M
% Asn:
0
0
8
8
22
8
0
8
0
0
0
0
0
0
8
% N
% Pro:
15
8
0
0
8
29
15
0
8
8
0
8
8
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
8
8
0
0
8
% Q
% Arg:
8
8
0
8
0
0
8
0
8
0
0
8
0
0
8
% R
% Ser:
8
8
15
8
15
0
15
36
0
8
8
0
0
8
0
% S
% Thr:
15
22
0
8
8
8
29
0
0
8
22
8
22
8
8
% T
% Val:
0
8
0
8
0
0
0
8
15
0
0
8
8
15
22
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
8
0
0
15
0
15
22
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _