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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDK1
All Species:
3.03
Human Site:
S397
Identified Species:
5.13
UniProt:
Q7Z5N4
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z5N4
NP_689957.3
2213
242076
S397
A
E
P
E
S
R
I
S
A
E
V
E
E
T
V
Chimpanzee
Pan troglodytes
XP_518946
2168
238269
T358
I
S
A
E
V
E
E
T
V
D
I
G
C
Q
A
Rhesus Macaque
Macaca mulatta
XP_001105243
2118
232418
A342
E
P
E
S
R
I
S
A
E
V
E
E
T
V
D
Dog
Lupus familis
XP_547004
2144
235913
I361
W
Y
K
D
A
I
S
I
S
K
L
Q
N
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q3UH53
2193
240287
L379
A
E
P
E
S
R
I
L
G
E
V
E
E
T
M
Rat
Rattus norvegicus
XP_001073292
2181
239558
L367
A
E
P
E
S
R
I
L
G
E
V
E
E
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513017
2131
235273
S358
Y
K
L
L
M
S
G
S
L
Q
I
Q
K
L
H
Chicken
Gallus gallus
Q8AV58
2169
239459
I358
E
V
E
K
D
V
D
I
L
C
Q
A
M
G
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_686686
2126
234665
L354
K
I
I
S
S
M
G
L
Q
V
R
K
L
Q
P
Tiger Blowfish
Takifugu rubipres
Q98902
1277
141937
Fruit Fly
Dros. melanogaster
O97394
2224
246236
G372
P
M
R
A
E
T
F
G
E
F
G
G
Q
V
Q
Honey Bee
Apis mellifera
XP_623565
2176
242722
V358
V
T
L
P
C
D
V
V
G
V
P
P
P
K
I
Nematode Worm
Caenorhab. elegans
Q9N3X8
2325
259146
D374
Q
R
G
K
L
T
I
D
R
I
K
Q
D
D
F
Sea Urchin
Strong. purpuratus
XP_781559
2931
322437
R395
T
M
G
N
S
R
F
R
M
E
D
D
G
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.7
91.5
86.7
N.A.
89.7
87.3
N.A.
79.6
78.9
N.A.
66
20.5
36.3
36.3
26.1
20.7
Protein Similarity:
100
96.1
93
91.5
N.A.
94
92
N.A.
87.8
87.8
N.A.
79.8
33.5
53.5
53.5
43.8
37.1
P-Site Identity:
100
6.6
6.6
0
N.A.
80
86.6
N.A.
6.6
6.6
N.A.
6.6
0
0
0
6.6
20
P-Site Similarity:
100
26.6
13.3
40
N.A.
86.6
86.6
N.A.
40
13.3
N.A.
13.3
0
6.6
13.3
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
0
8
8
8
0
0
8
8
0
0
8
0
0
8
% A
% Cys:
0
0
0
0
8
0
0
0
0
8
0
0
8
0
0
% C
% Asp:
0
0
0
8
8
8
8
8
0
8
8
8
8
8
8
% D
% Glu:
15
22
15
29
8
8
8
0
15
29
8
29
22
0
0
% E
% Phe:
0
0
0
0
0
0
15
0
0
8
0
0
0
0
8
% F
% Gly:
0
0
15
0
0
0
15
8
22
0
8
15
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
8
8
8
0
0
15
29
15
0
8
15
0
0
0
8
% I
% Lys:
8
8
8
15
0
0
0
0
0
8
8
8
8
8
0
% K
% Leu:
0
0
15
8
8
0
0
22
15
0
8
0
8
8
8
% L
% Met:
0
15
0
0
8
8
0
0
8
0
0
0
8
0
8
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
8
8
22
8
0
0
0
0
0
0
8
8
8
8
8
% P
% Gln:
8
0
0
0
0
0
0
0
8
8
8
22
8
15
8
% Q
% Arg:
0
8
8
0
8
29
0
8
8
0
8
0
0
0
8
% R
% Ser:
0
8
0
15
36
8
15
15
8
0
0
0
0
8
0
% S
% Thr:
8
8
0
0
0
15
0
8
0
0
0
0
8
22
0
% T
% Val:
8
8
0
0
8
8
8
8
8
22
22
0
0
15
22
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _