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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SDK1 All Species: 13.94
Human Site: S759 Identified Species: 23.59
UniProt: Q7Z5N4 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z5N4 NP_689957.3 2213 242076 S759 G Q Y S A E T S R L M L P E E
Chimpanzee Pan troglodytes XP_518946 2168 238269 P719 E T S R L M L P E E P P S A P
Rhesus Macaque Macaca mulatta XP_001105243 2118 232418 S703 G Q Y S A E T S R L M L P E E
Dog Lupus familis XP_547004 2144 235913 Q722 T N Q S I M V Q W Q P P P E T
Cat Felis silvestris
Mouse Mus musculus Q3UH53 2193 240287 S741 G Q Y S T E T S R L M L P E E
Rat Rattus norvegicus XP_001073292 2181 239558 S729 G Q Y S T E T S R L M L P E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513017 2131 235273 G719 E H N G I L H G Y N L R Y R L
Chicken Gallus gallus Q8AV58 2169 239459 P719 R L M L P E E P P S A P P K N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_686686 2126 234665 V715 N G V L R G Y V L R Y R L A G
Tiger Blowfish Takifugu rubipres Q98902 1277 141937
Fruit Fly Dros. melanogaster O97394 2224 246236 N746 G S P S E P S N V V E L P Q E
Honey Bee Apis mellifera XP_623565 2176 242722 E720 N V V V L P Q E P P S G P P V
Nematode Worm Caenorhab. elegans Q9N3X8 2325 259146 S745 K P S L P S Y S V T M P Q Q P
Sea Urchin Strong. purpuratus XP_781559 2931 322437 N756 S E K S E A S N V V H L P E E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.7 91.5 86.7 N.A. 89.7 87.3 N.A. 79.6 78.9 N.A. 66 20.5 36.3 36.3 26.1 20.7
Protein Similarity: 100 96.1 93 91.5 N.A. 94 92 N.A. 87.8 87.8 N.A. 79.8 33.5 53.5 53.5 43.8 37.1
P-Site Identity: 100 0 100 20 N.A. 93.3 93.3 N.A. 0 13.3 N.A. 0 0 33.3 6.6 13.3 33.3
P-Site Similarity: 100 0 100 20 N.A. 93.3 93.3 N.A. 6.6 20 N.A. 0 0 60 6.6 20 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 15 8 0 0 0 0 8 0 0 15 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 15 8 0 0 15 36 8 8 8 8 8 0 0 43 43 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 36 8 0 8 0 8 0 8 0 0 0 8 0 0 8 % G
% His: 0 8 0 0 0 0 8 0 0 0 8 0 0 0 0 % H
% Ile: 0 0 0 0 15 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 8 0 8 0 0 0 0 0 0 0 0 0 0 8 0 % K
% Leu: 0 8 0 22 15 8 8 0 8 29 8 43 8 0 8 % L
% Met: 0 0 8 0 0 15 0 0 0 0 36 0 0 0 0 % M
% Asn: 15 8 8 0 0 0 0 15 0 8 0 0 0 0 8 % N
% Pro: 0 8 8 0 15 15 0 15 15 8 15 29 65 8 15 % P
% Gln: 0 29 8 0 0 0 8 8 0 8 0 0 8 15 0 % Q
% Arg: 8 0 0 8 8 0 0 0 29 8 0 15 0 8 0 % R
% Ser: 8 8 15 50 0 8 15 36 0 8 8 0 8 0 0 % S
% Thr: 8 8 0 0 15 0 29 0 0 8 0 0 0 0 8 % T
% Val: 0 8 15 8 0 0 8 8 22 15 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 0 29 0 0 0 15 0 8 0 8 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _