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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SDK1 All Species: 19.7
Human Site: S769 Identified Species: 33.33
UniProt: Q7Z5N4 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z5N4 NP_689957.3 2213 242076 S769 M L P E E P P S A P P K N I V
Chimpanzee Pan troglodytes XP_518946 2168 238269 N729 P P S A P P K N I V A S G R T
Rhesus Macaque Macaca mulatta XP_001105243 2118 232418 S713 M L P E E P P S A P P K N I V
Dog Lupus familis XP_547004 2144 235913 N732 P P P E T E H N G V L R G Y I
Cat Felis silvestris
Mouse Mus musculus Q3UH53 2193 240287 S751 M L P E E P P S A P P K N I V
Rat Rattus norvegicus XP_001073292 2181 239558 S739 M L P E E P P S A P P K N I V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513017 2131 235273 L729 L R Y R L A G L P G E Y Q H R
Chicken Gallus gallus Q8AV58 2169 239459 A729 A P P K N I V A S G R T N Q S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_686686 2126 234665 G725 Y R L A G L P G E Y Q Q K N I
Tiger Blowfish Takifugu rubipres Q98902 1277 141937
Fruit Fly Dros. melanogaster O97394 2224 246236 S756 E L P Q E A P S G P P V G F V
Honey Bee Apis mellifera XP_623565 2176 242722 V730 S G P P V G F V G S A R S S S
Nematode Worm Caenorhab. elegans Q9N3X8 2325 259146 A755 M P Q Q P P S A A P R N V A A
Sea Urchin Strong. purpuratus XP_781559 2931 322437 T766 H L P E E L P T A P P Q E V D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.7 91.5 86.7 N.A. 89.7 87.3 N.A. 79.6 78.9 N.A. 66 20.5 36.3 36.3 26.1 20.7
Protein Similarity: 100 96.1 93 91.5 N.A. 94 92 N.A. 87.8 87.8 N.A. 79.8 33.5 53.5 53.5 43.8 37.1
P-Site Identity: 100 6.6 100 13.3 N.A. 100 100 N.A. 0 13.3 N.A. 6.6 0 53.3 6.6 26.6 53.3
P-Site Similarity: 100 13.3 100 33.3 N.A. 100 100 N.A. 6.6 33.3 N.A. 20 0 60 20 40 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 15 0 15 0 15 43 0 15 0 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % D
% Glu: 8 0 0 43 43 8 0 0 8 0 8 0 8 0 0 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 0 0 0 8 0 % F
% Gly: 0 8 0 0 8 8 8 8 22 15 0 0 22 0 0 % G
% His: 8 0 0 0 0 0 8 0 0 0 0 0 0 8 0 % H
% Ile: 0 0 0 0 0 8 0 0 8 0 0 0 0 29 15 % I
% Lys: 0 0 0 8 0 0 8 0 0 0 0 29 8 0 0 % K
% Leu: 8 43 8 0 8 15 0 8 0 0 8 0 0 0 0 % L
% Met: 36 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 0 15 0 0 0 8 36 8 0 % N
% Pro: 15 29 65 8 15 43 50 0 8 50 43 0 0 0 0 % P
% Gln: 0 0 8 15 0 0 0 0 0 0 8 15 8 8 0 % Q
% Arg: 0 15 0 8 0 0 0 0 0 0 15 15 0 8 8 % R
% Ser: 8 0 8 0 0 0 8 36 8 8 0 8 8 8 15 % S
% Thr: 0 0 0 0 8 0 0 8 0 0 0 8 0 0 8 % T
% Val: 0 0 0 0 8 0 8 8 0 15 0 8 8 8 36 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 8 0 0 0 0 0 0 8 0 8 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _