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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SDK1 All Species: 19.39
Human Site: S991 Identified Species: 32.82
UniProt: Q7Z5N4 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z5N4 NP_689957.3 2213 242076 S991 L D T S L K V S W Q E P L E K
Chimpanzee Pan troglodytes XP_518946 2168 238269 S946 L D T S L K V S W Q E P L E K
Rhesus Macaque Macaca mulatta XP_001105243 2118 232418 T930 S F T E I L D T S L K V S W Q
Dog Lupus familis XP_547004 2144 235913 N949 S W E V Y G R N G S R L T H T
Cat Felis silvestris
Mouse Mus musculus Q3UH53 2193 240287 S973 L D T S L K V S W Q E P L E R
Rat Rattus norvegicus XP_001073292 2181 239558 S961 L D T S L K V S W Q E P L E R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513017 2131 235273 Y946 L N S T T H E Y K I K G L S S
Chicken Gallus gallus Q8AV58 2169 239459 E946 S L K V S W Q E P V E K N G I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_686686 2126 234665 K942 A N T T L D Y K V T G L T S L
Tiger Blowfish Takifugu rubipres Q98902 1277 141937 P93 K D G E E F D P S S D P E M K
Fruit Fly Dros. melanogaster O97394 2224 246236 L988 S D R S V K V L W A P P R A S
Honey Bee Apis mellifera XP_623565 2176 242722 K952 S D R S L T V K W N P P Q E I
Nematode Worm Caenorhab. elegans Q9N3X8 2325 259146 T978 M Y N G A V I T W N S P L K Q
Sea Urchin Strong. purpuratus XP_781559 2931 322437 A1287 Q E S S V T I A W N E P L L P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.7 91.5 86.7 N.A. 89.7 87.3 N.A. 79.6 78.9 N.A. 66 20.5 36.3 36.3 26.1 20.7
Protein Similarity: 100 96.1 93 91.5 N.A. 94 92 N.A. 87.8 87.8 N.A. 79.8 33.5 53.5 53.5 43.8 37.1
P-Site Identity: 100 100 6.6 0 N.A. 93.3 93.3 N.A. 13.3 6.6 N.A. 13.3 20 40 46.6 20 33.3
P-Site Similarity: 100 100 33.3 6.6 N.A. 100 100 N.A. 40 6.6 N.A. 26.6 26.6 46.6 46.6 53.3 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 8 0 0 8 0 8 0 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 50 0 0 0 8 15 0 0 0 8 0 0 0 0 % D
% Glu: 0 8 8 15 8 0 8 8 0 0 43 0 8 36 0 % E
% Phe: 0 8 0 0 0 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 8 0 8 0 0 8 0 8 8 0 8 0 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 0 0 0 8 0 15 0 0 8 0 0 0 0 15 % I
% Lys: 8 0 8 0 0 36 0 15 8 0 15 8 0 8 22 % K
% Leu: 36 8 0 0 43 8 0 8 0 8 0 15 50 8 8 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 15 8 0 0 0 0 8 0 22 0 0 8 0 0 % N
% Pro: 0 0 0 0 0 0 0 8 8 0 15 65 0 0 8 % P
% Gln: 8 0 0 0 0 0 8 0 0 29 0 0 8 0 15 % Q
% Arg: 0 0 15 0 0 0 8 0 0 0 8 0 8 0 15 % R
% Ser: 36 0 15 50 8 0 0 29 15 15 8 0 8 15 15 % S
% Thr: 0 0 43 15 8 15 0 15 0 8 0 0 15 0 8 % T
% Val: 0 0 0 15 15 8 43 0 8 8 0 8 0 0 0 % V
% Trp: 0 8 0 0 0 8 0 0 58 0 0 0 0 8 0 % W
% Tyr: 0 8 0 0 8 0 8 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _